ID A0A182M9N2_9DIPT Unreviewed; 381 AA.
AC A0A182M9N2;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Maelstrom domain-containing protein {ECO:0000259|Pfam:PF13017};
OS Anopheles culicifacies.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles; culicifacies species complex.
OX NCBI_TaxID=139723 {ECO:0000313|EnsemblMetazoa:ACUA012897-PA, ECO:0000313|Proteomes:UP000075883};
RN [1] {ECO:0000313|Proteomes:UP000075883}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A-37 {ECO:0000313|Proteomes:UP000075883};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles culicifacies species A.";
RL Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ACUA012897-PA}
RP IDENTIFICATION.
RC STRAIN=A-37 {ECO:0000313|EnsemblMetazoa:ACUA012897-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the maelstrom family.
CC {ECO:0000256|ARBA:ARBA00007057}.
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DR EMBL; AXCM01000726; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A182M9N2; -.
DR EnsemblMetazoa; ACUA012897-RA; ACUA012897-PA; ACUA012897.
DR VEuPathDB; VectorBase:ACUA012897; -.
DR OrthoDB; 3137062at2759; -.
DR Proteomes; UP000075883; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0060964; P:regulation of miRNA-mediated gene silencing; IEA:InterPro.
DR GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:UniProtKB-KW.
DR InterPro; IPR024970; Maelstrom.
DR InterPro; IPR039259; Protein_maelstrom.
DR PANTHER; PTHR21358; PROTEIN MAELSTROM HOMOLOG; 1.
DR PANTHER; PTHR21358:SF4; PROTEIN MAELSTROM HOMOLOG; 1.
DR Pfam; PF13017; Maelstrom; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..381
FT /note="Maelstrom domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008128016"
FT DOMAIN 102..303
FT /note="Maelstrom"
FT /evidence="ECO:0000259|Pfam:PF13017"
FT REGION 321..358
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 326..351
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 381 AA; 43015 MW; 3E172CC813EF9C60 CRC64;
MRSIQVMLFL TLISTRLQTN AARKKYLRQH HHVPPQMKSG ERREYVLQAK EYLDEKECLS
VYYTLARERA ELEAARCKEA NKVGLMNSLF VKRLEDSGAR HGTYLPAELA IIRYSLKGGV
NDQLHMLIDP GVISLCDEYT ALQHSKKTHA LRIPPDALGL SDYDEIAEKI LSFTAAKTQP
TLLFTDADNV PIVEGMLDEF LEDHNEATSM LYVCSLAELF CKLQVAEMDP SSAVPSVEMV
RKCLDEDVYS NTVGISCEFH ESRGLVKHCA LSQCVRWAYT LSNNCCPSMN IELLPGKHIP
MDNQMGNDAV VLTSDASEIE TNEGESDYTQ RNANELPEQT PSRNESIQAA ESLIPATPKK
ETRILKRLRR FREMLAKEAQ K
//
