ID A0A182MLV8_9DIPT Unreviewed; 537 AA.
AC A0A182MLV8;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 22-FEB-2023, entry version 29.
DE RecName: Full=Arf-GAP domain-containing protein {ECO:0000259|PROSITE:PS50115};
OS Anopheles culicifacies.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles; culicifacies species complex.
OX NCBI_TaxID=139723 {ECO:0000313|EnsemblMetazoa:ACUA021387-PA, ECO:0000313|Proteomes:UP000075883};
RN [1] {ECO:0000313|Proteomes:UP000075883}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A-37 {ECO:0000313|Proteomes:UP000075883};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles culicifacies species A.";
RL Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ACUA021387-PA}
RP IDENTIFICATION.
RC STRAIN=A-37 {ECO:0000313|EnsemblMetazoa:ACUA021387-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; AXCM01005695; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A182MLV8; -.
DR STRING; 139723.A0A182MLV8; -.
DR EnsemblMetazoa; ACUA021387-RA; ACUA021387-PA; ACUA021387.
DR VEuPathDB; VectorBase:ACUA021387; -.
DR OrthoDB; 1022106at2759; -.
DR Proteomes; UP000075883; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd08839; ArfGap_SMAP; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR InterPro; IPR044732; ArfGAP_SMAP1-like.
DR PANTHER; PTHR45705; FI20236P1; 1.
DR PANTHER; PTHR45705:SF1; FI20236P1; 1.
DR Pfam; PF01412; ArfGap; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00105; ArfGap; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR PROSITE; PS50115; ARFGAP; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00288}.
FT DOMAIN 18..136
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REGION 154..239
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 279..301
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 506..537
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..203
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 212..239
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 537 AA; 55526 MW; 682A84058E261182 CRC64;
MSRKNETERQ KQIQEKCQMM LTKMLRDDDN KYCVDCDAKG PRWASWNLGV FLCIRCAGIH
RNLGVHISRV KSVNLDSWTP EQVVSLEQMG NSRARAVYEA MIPDGFRRPQ TDSALESFIR
AKYEHKKYLA REWVPPPAPK VDWDREIDEE IERQKRKKKA SSSGGGGIGS VSGTLSLSSP
ADKKGVGSSG ASPSSTGSSM SNAAVPKLKA PASSMKSSSR TSGVSLNTSS SSSSSSAVTT
SDASTALPAS GSAAGGNAGN TSAGTDLLGL SLGEGSVAMN HNSGGSASKT SNGLSSTASS
NGIDLLERKN ADTDDLAKVE ADFFNQSGPG NGVDASGKLT KDKIMALYGS APSTVGPTVG
GGFGGPAFGG FQQAGSTFPP APNAPAASVP FNGGMMPANA FGAFQTFPGL NGVPGTGAPG
QYPMMGGGVA PSQMVYNNGG VAAPNMMAAG SMFNAQTGGA PAQPLGMVPP YGAMPQYGGA
GFPPMVGMPQ HGQAMPAAAV FANFPKAVPQ QQQQQQQQQQ DKLSNQFGTM NLRDVWQ
//
