ID A0A182MMK2_9DIPT Unreviewed; 586 AA.
AC A0A182MMK2;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 22-FEB-2023, entry version 26.
DE RecName: Full=Conserved oligomeric Golgi complex subunit 8 {ECO:0000256|ARBA:ARBA00020983, ECO:0000256|PIRNR:PIRNR015415};
DE Short=COG complex subunit 8 {ECO:0000256|PIRNR:PIRNR015415};
DE AltName: Full=Component of oligomeric Golgi complex 8 {ECO:0000256|ARBA:ARBA00031347, ECO:0000256|PIRNR:PIRNR015415};
OS Anopheles culicifacies.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles; culicifacies species complex.
OX NCBI_TaxID=139723 {ECO:0000313|EnsemblMetazoa:ACUA021887-PA, ECO:0000313|Proteomes:UP000075883};
RN [1] {ECO:0000313|Proteomes:UP000075883}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A-37 {ECO:0000313|Proteomes:UP000075883};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles culicifacies species A.";
RL Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ACUA021887-PA}
RP IDENTIFICATION.
RC STRAIN=A-37 {ECO:0000313|EnsemblMetazoa:ACUA021887-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBUNIT: Component of the conserved oligomeric Golgi complex which is
CC composed of eight different subunits and is required for normal Golgi
CC morphology and localization. {ECO:0000256|PIRNR:PIRNR015415}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004395, ECO:0000256|PIRNR:PIRNR015415};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004395,
CC ECO:0000256|PIRNR:PIRNR015415}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the COG8 family. {ECO:0000256|ARBA:ARBA00006419,
CC ECO:0000256|PIRNR:PIRNR015415}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AXCM01007124; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A182MMK2; -.
DR STRING; 139723.A0A182MMK2; -.
DR EnsemblMetazoa; ACUA021887-RA; ACUA021887-PA; ACUA021887.
DR VEuPathDB; VectorBase:ACUA021887; -.
DR OrthoDB; 1442148at2759; -.
DR Proteomes; UP000075883; Unassembled WGS sequence.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0017119; C:Golgi transport complex; IEA:UniProtKB-UniRule.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR InterPro; IPR007255; COG8.
DR InterPro; IPR016632; COG8_Metazoal_Plant.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR PANTHER; PTHR21311; CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 8; 1.
DR PANTHER; PTHR21311:SF0; CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 8; 1.
DR Pfam; PF04124; Dor1; 1.
DR PIRSF; PIRSF015415; COG8; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
PE 3: Inferred from homology;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034,
KW ECO:0000256|PIRNR:PIRNR015415};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR015415};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR015415};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR015415}.
FT REGION 395..415
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 560..586
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 586 AA; 67207 MW; 2D60B0C10178A349 CRC64;
MDYENDKVLK FIFPDDYEEL SSQDTSDVVD YLLKLGTYKT EDLKKEKVRL QDEHRQNVEQ
TQDLAISHYH TFIRTAESSR EIYREFVDTE RKLDCLSDKW PKFIAACQTF QQGSADINAA
RRLNSLTLMR NAELLEILEL PQLMDSCIRE GKYEEALELS SYVQRLTAKH GSIPVIANIN
EAVEAAWHTM LMQLLAQLRT DLQLPKCLQV VGYLRRMQAF STSELKLKFL QTRTSWLKDL
LATIPTEDTH VHLTKTIEAT RVHLFNIITQ YRAIFPDDED TYNPLGVTIG NERTVGDEGK
IFHSWLHDQI MEFVRSLERD LASNDITSYD TILGQCMYFG LSFSRVGIDF RALVAPVFVR
VIGNRFRLSI ARATLQFEQD IERYTLINKV PSMIRRQRDD RTSRPDDSGS VQPPETLLDF
EPLAIYCNEI LTIFNDLRLC SPVALATMAT ELLESSLEQV CRGILGFYRQ EQQAFAPTER
ECFIRLCSCF AYDLIPYLQR CIHVLFPPAT LASQLGINVL TLQKHGVTYL RQKKILEPIA
YLLPDRIDTV IKQVAEISVD STSDQETTEA TEVAPSSESV EASATE
//
