ID A0A182MN44_9DIPT Unreviewed; 603 AA.
AC A0A182MN44;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Gamma-glutamyltransferase {ECO:0008006|Google:ProtNLM};
OS Anopheles culicifacies.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles; culicifacies species complex.
OX NCBI_TaxID=139723 {ECO:0000313|EnsemblMetazoa:ACUA022237-PA, ECO:0000313|Proteomes:UP000075883};
RN [1] {ECO:0000313|Proteomes:UP000075883}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A-37 {ECO:0000313|Proteomes:UP000075883};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles culicifacies species A.";
RL Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ACUA022237-PA}
RP IDENTIFICATION.
RC STRAIN=A-37 {ECO:0000313|EnsemblMetazoa:ACUA022237-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; AXCM01000683; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A182MN44; -.
DR STRING; 139723.A0A182MN44; -.
DR EnsemblMetazoa; ACUA022237-RA; ACUA022237-PA; ACUA022237.
DR VEuPathDB; VectorBase:ACUA022237; -.
DR OrthoDB; 2910309at2759; -.
DR Proteomes; UP000075883; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0036374; F:glutathione hydrolase activity; IEA:InterPro.
DR GO; GO:0006751; P:glutathione catabolic process; IEA:InterPro.
DR Gene3D; 1.10.246.130; -; 1.
DR Gene3D; 3.60.20.40; -; 1.
DR InterPro; IPR043138; GGT_lsub_C.
DR InterPro; IPR000101; GGT_peptidase.
DR InterPro; IPR043137; GGT_ssub.
DR InterPro; IPR029055; Ntn_hydrolases_N.
DR PANTHER; PTHR11686; GAMMA GLUTAMYL TRANSPEPTIDASE; 1.
DR PANTHER; PTHR11686:SF75; GAMMA-GLUTAMYL TRANSPEPTIDASE, ISOFORM A; 1.
DR Pfam; PF01019; G_glu_transpept; 1.
DR PRINTS; PR01210; GGTRANSPTASE.
DR SUPFAM; SSF56235; N-terminal nucleophile aminohydrolases (Ntn hydrolases); 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 33..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT ACT_SITE 410
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR600101-1"
SQ SEQUENCE 603 AA; 65587 MW; 22A62961DD7F50B1 CRC64;
MGQSQTNSNA GQQYKLCYGM QSSQELNINK KKLLLLSVLA AVVIVALVVG LTVGLRSRDD
GEKSHARLTG AAVTSNGIEC AGIGEDILRR NGSAVDAAIA TLFCEGVTCP QSMGIGGGFL
ATIYIRETNT AQALVSREVA PAAATENMYV NQSSVSGGLA IAVPGEVKGY WTLHQKYGRL
EWKELVEPTI RLCREGHLVT GYLERILKGR EERIRNEPTL RDVFINPATQ QTWREGDKLK
RPTLADTLEV IAIEGADALY SRNGTLLPKL MRDLKLLGSI ITEDDFYNYE PRWVAPVQTS
IRKSSQVYSI PLPGSGAILN YMLNILDNYD DLRQGDPVSW HRIVESFKHG YGMRTRLGDP
AYVPGIEDNL EKLSSKTYAR YIFETIKDDR THSEYAHYGA EFSNERDHGT AHVSVLAPNG
DAVAITSTIN NVLGAMVRST STGIVLNDEM DDFATPGLIN SYGLPASPAN YIVPGKAPLS
SMTPTIITDE TGDVRIVAGS AGGSRITTAT MQLIVRHMIF GETLDTIINT PRMHHQLAPM
SIEYEKGFDP VVIAGLQARG HVCNEAASDG GFAALTAIVR HADNLIEATY DPRRSGSISI
LKS
//
