ID   A0A182MU11_9DIPT        Unreviewed;       525 AA.
AC   A0A182MU11;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   24-JAN-2024, entry version 30.
DE   RecName: Full=WD repeat-containing protein 55 homolog {ECO:0000256|ARBA:ARBA00023478};
OS   Anopheles culicifacies.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles; culicifacies species complex.
OX   NCBI_TaxID=139723 {ECO:0000313|EnsemblMetazoa:ACUA026236-PA, ECO:0000313|Proteomes:UP000075883};
RN   [1] {ECO:0000313|Proteomes:UP000075883}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A-37 {ECO:0000313|Proteomes:UP000075883};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles culicifacies species A.";
RL   Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:ACUA026236-PA}
RP   IDENTIFICATION.
RC   STRAIN=A-37 {ECO:0000313|EnsemblMetazoa:ACUA026236-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the WD repeat WDR55 family.
CC       {ECO:0000256|ARBA:ARBA00007625}.
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DR   EMBL; AXCM01009415; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A182MU11; -.
DR   STRING; 139723.A0A182MU11; -.
DR   EnsemblMetazoa; ACUA026236-RA; ACUA026236-PA; ACUA026236.
DR   VEuPathDB; VectorBase:ACUA026236; -.
DR   OrthoDB; 153323at2759; -.
DR   Proteomes; UP000075883; Unassembled WGS sequence.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR   InterPro; IPR024977; Apc4-like_WD40_dom.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR44019; WD REPEAT-CONTAINING PROTEIN 55; 1.
DR   PANTHER; PTHR44019:SF20; WD REPEAT-CONTAINING PROTEIN 55; 1.
DR   Pfam; PF12894; ANAPC4_WD40; 1.
DR   Pfam; PF00400; WD40; 2.
DR   SMART; SM00320; WD40; 5.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 2.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW   ProRule:PRU00221}.
FT   DOMAIN          207..281
FT                   /note="Anaphase-promoting complex subunit 4-like WD40"
FT                   /evidence="ECO:0000259|Pfam:PF12894"
FT   REPEAT          283..323
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          451..485
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REGION          1..35
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          67..172
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..25
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        83..100
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        101..133
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        137..152
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   525 AA;  58021 MW;  B673C92525BFDD53 CRC64;
     MMVPTETLTT NTVSGSSGRN FHSPYFRDSS DSEDDAEIDI EQLGIPHFLT ARTEDFFDLV
     EYSSDGEDGF AGTPVLSVMD DSDSDSTYEE EDDSQMSDTS SDSDMEDQTT NAESGNKVET
     AKRTSNAEGT SDSDSGSDAE DGNKDETAKK ASDGENASAS GSSHRVIDDY DEDMEDDEVV
     KAIISEIKKP RSKPPDIHME DFVVDLSFHP SEDMLAVGTS VGDVLMYKYS NEQNVLAATH
     ELHTKAVRCV EYTCDGTSLI STGRERSIVV ADTETGKFKR FWEGAHDEPV YSMAVIGEHL
     FATGDDNGMV KLWDLRQKDA VFSLRPVEDF ISSILSNNSQ QKYLLMTSGD GLLTTINIAQ
     RKMYVQSEPY EEELNCMGTF KRESKLIVGT SKGNYYTFNW GQFAYHCDAF TGPKASANRM
     VPITEQIAVM AGEDGFIRAM HLVPGRVLGI VGQHSMAVDA MDISGSGELI ASSSHDNDVR
     FWNIKYFEDF DGIKYNSKPD NRTLKHNLPS SQRVNAKDFF AGLNE
//