ID A0A182MV98_9DIPT Unreviewed; 467 AA.
AC A0A182MV98;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 22-FEB-2023, entry version 27.
DE RecName: Full=C2 domain-containing protein {ECO:0000259|PROSITE:PS50004};
OS Anopheles culicifacies.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles; culicifacies species complex.
OX NCBI_TaxID=139723 {ECO:0000313|EnsemblMetazoa:ACUA027096-PA, ECO:0000313|Proteomes:UP000075883};
RN [1] {ECO:0000313|Proteomes:UP000075883}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A-37 {ECO:0000313|Proteomes:UP000075883};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles culicifacies species A.";
RL Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ACUA027096-PA}
RP IDENTIFICATION.
RC STRAIN=A-37 {ECO:0000313|EnsemblMetazoa:ACUA027096-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; AXCM01002852; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A182MV98; -.
DR STRING; 139723.A0A182MV98; -.
DR EnsemblMetazoa; ACUA027096-RA; ACUA027096-PA; ACUA027096.
DR VEuPathDB; VectorBase:ACUA027096; -.
DR OrthoDB; 590187at2759; -.
DR Proteomes; UP000075883; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd08388; C2A_Synaptotagmin-4-11; 1.
DR CDD; cd08404; C2B_Synaptotagmin-4; 1.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR001565; Synaptotagmin.
DR PANTHER; PTHR10024:SF369; FI18813P1; 1.
DR PANTHER; PTHR10024; SYNAPTOTAGMIN; 1.
DR Pfam; PF00168; C2; 2.
DR PRINTS; PR00360; C2DOMAIN.
DR PRINTS; PR00399; SYNAPTOTAGMN.
DR SMART; SM00239; C2; 2.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 2.
DR PROSITE; PS50004; C2; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 15..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 164..307
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 324..463
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT REGION 52..162
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..125
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 467 AA; 51244 MW; 849EC014BB2E1A24 CRC64;
MENELAAKFM MLLDYVVLIS VVPAVLGLTA AAILAVTACF CARRFRRQNK KAGHEASSLP
FQPPRPPKAV RSPSGQPPQY LKKSPSPTSI KPLPGHLPAQ SPTEQTTVAA TTTTTTTTSI
VPPTKYTEEN ELIPKNAQLE PKSPDVSELG DPCSEPGDGS EHGKLGTIVF KLRFLADRSA
LVVSVVRCRG LPGKNHGSAI AELSTMAGGT LCNGSANGKQ TATDPYVKLQ LLPDKQHKVK
TRVLRNTRNP VYDEDFTFYG LTLNELAGMS LHFVVLSFDR YSRDDVIGEV VCPLSGIDLQ
QIENQQVALS REIQPRSLKI RAQGRGELLI SLCWQPAAAR LTVVLLKARN LPRMDVTGLA
DPYVKIYLLY NGQRIAKKKT HVKKRTLSPV FNESFAFDIP TTEGAGATLD GVSLELMLLD
WDRVTKNEVI GRLELGGPRS NGSALNHWKE VCNSPRRQIA DWHKLRE
//
