ID A0A182MWZ6_9DIPT Unreviewed; 580 AA.
AC A0A182MWZ6;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=DUF4746 domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Anopheles culicifacies.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles; culicifacies species complex.
OX NCBI_TaxID=139723 {ECO:0000313|EnsemblMetazoa:ACUA028332-PA, ECO:0000313|Proteomes:UP000075883};
RN [1] {ECO:0000313|Proteomes:UP000075883}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A-37 {ECO:0000313|Proteomes:UP000075883};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles culicifacies species A.";
RL Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ACUA028332-PA}
RP IDENTIFICATION.
RC STRAIN=A-37 {ECO:0000313|EnsemblMetazoa:ACUA028332-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; AXCM01002401; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A182MWZ6; -.
DR STRING; 139723.A0A182MWZ6; -.
DR EnsemblMetazoa; ACUA028332-RA; ACUA028332-PA; ACUA028332.
DR VEuPathDB; VectorBase:ACUA028332; -.
DR OrthoDB; 5481442at2759; -.
DR Proteomes; UP000075883; Unassembled WGS sequence.
DR CDD; cd02948; TRX_NDPK; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR031827; DUF4746.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR017937; Thioredoxin_CS.
DR InterPro; IPR013766; Thioredoxin_domain.
DR PANTHER; PTHR46135; NME/NM23 FAMILY MEMBER 8; 1.
DR PANTHER; PTHR46135:SF3; THIOREDOXIN DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF15928; DUF4746; 1.
DR Pfam; PF00085; Thioredoxin; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS00194; THIOREDOXIN_1; 1.
PE 4: Predicted;
FT DOMAIN 14..109
FT /note="Thioredoxin"
FT /evidence="ECO:0000259|Pfam:PF00085"
FT DOMAIN 237..499
FT /note="DUF4746"
FT /evidence="ECO:0000259|Pfam:PF15928"
FT REGION 319..339
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 497..580
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 319..335
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 520..537
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 553..570
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 580 AA; 65283 MW; 79011D6C6CACCE82 CRC64;
MAKKGGVQQL QTEINTDDEF EKFLERDGLL VLDVYTEWCG PCVGMIGSLK KIKLELGGDN
LQLAICKSDE ISALKRFRNK SEPTWLFASH GKIVNLMFGT NVPKLINLIT EELDIELKCR
AGEVERTYYE LWELTPEEQE REDVRQEREE EVARIEKEAA AKKRLDYITH VTDEIMTNIP
DMGITLFMPH VHKDVFKKLH DHAEKHDLHM KEKRLVHLNP KMLEVLHFEC ENRLADDVFE
QIYYKDIQAY VWKLTEGETR SPEEVIGAFV KIITEPVEVL DADGNVEKVI PRMIEPLEML
YNANDGTWKM VSKLPPQKSA SSIATTNSSE SSQNASKETF DEEACPRLII PGVWTPTNRR
ANAALFYLLF RHLTEHFLPP DPVPEPPHIC MVFDAYKKRD VLEVAMNEKY KTQVMAFGYF
STGDPKTAEL IAKTTERYTT KRPNVNDKLI MKVSKATSHA MLALTAMGPC YVSQNAVEGQ
EECATLFPPN YNFVEEENET GEVEKKKHKK KRRGKKSDTS VSSAADSAVS TTPSAEPGAD
GQGELGTIGE GSTGEEGETT SSSQNSPEKT GGDPEEGAPS
//
