ID   A0A182MXT5_9DIPT        Unreviewed;       315 AA.
AC   A0A182MXT5;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   22-FEB-2023, entry version 24.
DE   RecName: Full=Thioredoxin domain-containing protein {ECO:0000259|Pfam:PF00085};
OS   Anopheles dirus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=7168 {ECO:0000313|EnsemblMetazoa:ADIR000188-PA, ECO:0000313|Proteomes:UP000075884};
RN   [1] {ECO:0000313|Proteomes:UP000075884}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WRAIR2 {ECO:0000313|Proteomes:UP000075884};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Walton C., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles dirus WRAIR2.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:ADIR000188-PA}
RP   IDENTIFICATION.
RC   STRAIN=WRAIR2 {ECO:0000313|EnsemblMetazoa:ADIR000188-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
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DR   AlphaFoldDB; A0A182MXT5; -.
DR   STRING; 7168.A0A182MXT5; -.
DR   EnsemblMetazoa; ADIR000188-RA; ADIR000188-PA; ADIR000188.
DR   VEuPathDB; VectorBase:ADIR000188; -.
DR   OrthoDB; 3678801at2759; -.
DR   Proteomes; UP000075884; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR013766; Thioredoxin_domain.
DR   InterPro; IPR042418; TXNDC15.
DR   PANTHER; PTHR14684:SF2; THIOREDOXIN DOMAIN-CONTAINING PROTEIN 15; 1.
DR   PANTHER; PTHR14684; UNCHARACTERIZED; 1.
DR   Pfam; PF00085; Thioredoxin; 1.
DR   SUPFAM; SSF52833; Thioredoxin-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..315
FT                   /note="Thioredoxin domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5008128980"
FT   TRANSMEM        273..291
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          152..233
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000259|Pfam:PF00085"
SQ   SEQUENCE   315 AA;  35482 MW;  18BA23132EA2FC99 CRC64;
     MLSLKHTFCL IFLLFLANDA TAFRFKGLDF YAQLLNGEFL ESNPFGGGAS AAKADDKVED
     SAPRAVLQGQ WLQSTLYDRL TYKDKITCTL ADRSEHEDGL HPDGGRRSPL RVKCNPVEGN
     GTLYIITSLK DMVKGLAHYG NSTKRHEVGS CLLMLFYTKT CIHSAMVAPH FNALARHFPD
     LVVTAIDAYN FHFLNAEFGI VGLPTIMLFH QGRPLVKYNG TEITLTALAK FVTRHTGIEP
     RLANQKSSTT VLHYISDDFK GPLSNKVEFR TDYWLYVAWA FIVVCACYYF SKSSLYAQII
     EMIKRNWRES AAQHS
//