ID A0A182N2I7_9DIPT Unreviewed; 1467 AA.
AC A0A182N2I7;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=CKK domain-containing protein {ECO:0000259|PROSITE:PS51508};
OS Anopheles dirus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=7168 {ECO:0000313|EnsemblMetazoa:ADIR001845-PA, ECO:0000313|Proteomes:UP000075884};
RN [1] {ECO:0000313|Proteomes:UP000075884}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WRAIR2 {ECO:0000313|Proteomes:UP000075884};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Walton C., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles dirus WRAIR2.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ADIR001845-PA}
RP IDENTIFICATION.
RC STRAIN=WRAIR2 {ECO:0000313|EnsemblMetazoa:ADIR001845-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- DOMAIN: The CKK domain binds microtubules. {ECO:0000256|PROSITE-
CC ProRule:PRU00841}.
CC -!- SIMILARITY: Belongs to the CAMSAP1 family. {ECO:0000256|PROSITE-
CC ProRule:PRU00841}.
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DR STRING; 7168.A0A182N2I7; -.
DR EnsemblMetazoa; ADIR001845-RA; ADIR001845-PA; ADIR001845.
DR VEuPathDB; VectorBase:ADIR001845; -.
DR OrthoDB; 2918432at2759; -.
DR Proteomes; UP000075884; Unassembled WGS sequence.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-UniRule.
DR GO; GO:0005516; F:calmodulin binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0030507; F:spectrin binding; IEA:InterPro.
DR GO; GO:0031175; P:neuron projection development; IEA:InterPro.
DR Gene3D; 3.10.20.360; CKK domain; 1.
DR InterPro; IPR032940; CAMSAP.
DR InterPro; IPR031372; CAMSAP_CC1.
DR InterPro; IPR038209; CKK_dom_sf.
DR InterPro; IPR014797; CKK_domain.
DR InterPro; IPR011033; PRC_barrel-like_sf.
DR PANTHER; PTHR21595:SF0; PATRONIN; 1.
DR PANTHER; PTHR21595; UNCHARACTERIZED; 1.
DR Pfam; PF17095; CAMSAP_CC1; 1.
DR Pfam; PF08683; CAMSAP_CKK; 1.
DR SMART; SM01051; CAMSAP_CKK; 1.
DR SUPFAM; SSF50346; PRC-barrel domain; 1.
DR PROSITE; PS51508; CKK; 1.
PE 3: Inferred from homology;
KW Microtubule {ECO:0000256|PROSITE-ProRule:PRU00841}.
FT DOMAIN 1326..1460
FT /note="CKK"
FT /evidence="ECO:0000259|PROSITE:PS51508"
FT REGION 1..186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 288..311
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 416..497
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 529..599
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 645..687
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 723..928
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1072..1102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1137..1204
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1252..1319
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..29
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 57..76
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 131..159
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 288..307
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 416..439
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 448..497
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 529..555
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 572..599
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 779..823
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 831..861
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 892..917
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1137..1158
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1177..1204
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1467 AA; 162026 MW; B95EE3B9D46D3081 CRC64;
MQEPLVPARI RQAKEKTNND SKAEERGDSI PAGRPSNWEE SRKPSFSGRR SRRNSFSDDS
QLTIENFGGS QDQLNTVGRF ERERKISNTS LTSIEPVVPA RSSLADARGS IQFGYDTDSG
NEKQDRDTEK LSGSSSGTLR RHNSTTLHSN SSPMSHPAGD TTSGRGGGSV ERDAIDGDGT
STTGSVGGMA IAAAATVSDV ELTPRRKTSF AAVPNTTTWQ QQAISVQRMD DVDDAQPLED
ATKISTIKLK LEEKRRMIEQ EKRRIESAWT KQLQTVGKQA FLQAISKSKS GSNVAGEPDS
TAKESNDGAT IVDEEEGVVE KAERPCSLKD LDDHSKYEQK WNAQIIEPKK TPDLENMDLE
QYQVNNADIQ RLTQQQNQIQ AQTLQAQQLL HAQQIANLLN QQYGSQQSIP ATTYRPMNTQ
MFGSSPHLPQ QQSSPINYGM RPPSRDPYLS QPHQQQQQQQ QHTMQYINEQ GQYVQQQQQQ
SYGHHPNSHL VYSREQSQTQ LINDQNGGNQ YRTMSKESHQ YSSNPYLNME HHQQQQQQQQ
QFYHQDSNHY RDPYQPQQLQ HAPELKDPAQ PQQQPHGGQF FLHESNSTPP QPTQRRTWAQ
SAAAAGVPLG GSPLIPGRNA SDNNGGSMVD VNAWNHGPKT ATLGYNRSPA PSGGFSLHHN
GGGDGDSGYG GGSGRGGSGG SGGSQQSFQN LFEVHHPHHA HGQSAASPQH SKVRNQISQM
MISNGAGSPS AGGPMMVGGG GGDYRDNRSM PLSPPIDDMA PQSISFIGDE DTGDMEINTS
KGGGRNDSFS VRQQQQQQQQ LDALYGSSKS PAGMRNNGGT GGANVQDLDK HLSKLNITSG
NRTYRIPSPT RPSLNSNSFH DPQDDVNEKG FYISFDNEQP KRPKPPLRTK RSPKKDKPLA
GDSNEGDKRR DSMSDKPSTR ETNANNYGTY SVKTASSFSS SFNEEHNASH ARKSIIADNS
GVSPFEPVVH KVNVTGSGSA ASPSPMMMMH QHQQQDHVDR RYVGGLEDNL MSGNGHYSSH
NNSSDGYGSE TERKAKIVID VSNDPSSVDE MERKKEKIML LSLQRRQQAE EAKARKEIEA
MQRREKEREK EEERARKKEE QFARRQQILE AHKLKKAIEE AEREGKTIDR ELQLKHQQYQ
QQLHQTAHST TPTPAAKMRT QKLSRPRPKT IHVESGSVDL SEASSLSSRG KKGSNSNLTG
LGMHSASNTI RRDYYRGSQD SLAIREPPAT IERGRTLSRI SLAKGANFRG RKSNSLMNLC
DSDSGLGRAT PPRRAPSPGM GPSSRHLPSP SGPGSLPPGL ITKRRGFDDG SSDISSNASS
MMDYNGPRLY KQPATKSNRG IILNAVEYCV FPGAVNRDAK QKVLEKIARS EAKHFLVLFR
DAGCQFRALY GYWPENEQII KLYGTGPSQV DDVMFDKFFK YNSGGKCFTQ VHTKHLTVTI
DAFTIHNSLW QGKKANLPSK KDMALVI
//
