ID   A0A182N5E1_9DIPT        Unreviewed;       739 AA.
AC   A0A182N5E1;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   RecName: Full=AAA+ ATPase domain-containing protein {ECO:0000259|SMART:SM00382};
OS   Anopheles dirus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=7168 {ECO:0000313|EnsemblMetazoa:ADIR002860-PA, ECO:0000313|Proteomes:UP000075884};
RN   [1] {ECO:0000313|Proteomes:UP000075884}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WRAIR2 {ECO:0000313|Proteomes:UP000075884};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Walton C., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles dirus WRAIR2.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:ADIR002860-PA}
RP   IDENTIFICATION.
RC   STRAIN=WRAIR2 {ECO:0000313|EnsemblMetazoa:ADIR002860-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the AAA ATPase family.
CC       {ECO:0000256|ARBA:ARBA00006914}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A182N5E1; -.
DR   STRING; 7168.A0A182N5E1; -.
DR   EnsemblMetazoa; ADIR002860-RA; ADIR002860-PA; ADIR002860.
DR   VEuPathDB; VectorBase:ADIR002860; -.
DR   OrthoDB; 360215at2759; -.
DR   Proteomes; UP000075884; Unassembled WGS sequence.
DR   GO; GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   CDD; cd19502; RecA-like_PAN_like; 1.
DR   Gene3D; 1.10.8.60; -; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR041569; AAA_lid_3.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR003960; ATPase_AAA_CS.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR032501; Prot_ATP_ID_OB_2nd.
DR   InterPro; IPR002347; SDR_fam.
DR   PANTHER; PTHR23073; 26S PROTEASOME REGULATORY SUBUNIT; 1.
DR   PANTHER; PTHR23073:SF155; 26S PROTEASOME REGULATORY SUBUNIT 10B; 1.
DR   Pfam; PF00004; AAA; 1.
DR   Pfam; PF17862; AAA_lid_3; 1.
DR   Pfam; PF00106; adh_short; 1.
DR   Pfam; PF16450; Prot_ATP_ID_OB_C; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS00674; AAA; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Proteasome {ECO:0000256|ARBA:ARBA00022942}.
FT   DOMAIN          169..308
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   COILED          22..56
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   739 AA;  83613 MW;  2A083B770F99812E CRC64;
     MTVVDAAREK ALEDYRKKLL EHKEVESRLK EVRESLKELT KQFDKSENDL KALQSVGQIV
     GEVLKQLTED KFIVKATNGP RYVVGCRRQL DKTKLKSGTR VALDMTTLTI MRYLPREVDP
     LVYNMSHEDP GEVTYSAIGG LSEQIRELRE VIELPLLNPE LFLRVGITPP KGCLLYGPPG
     TGKTLLARAV ASQLDANFLK VVSSAIVDKY IGESARLIRE MFNYARDHQP CIIFMDEIDA
     IGGRRFSEGT SADREIQRTL MELLNQMDGF DSLGQVKMIM ATNRPDTLDP ALLRPGRLDR
     KIEIPLPNEQ ARLEILKIHA APIAKHGDID YEAVVKLSDN FNGADLRNVC TEAGLFAIRA
     EREYVIQEDF MKAVRKVADN KRLESKLDYK PNTPREHAEI AMGLFKKCCV LIGLGSVAYF
     VRWYYIGRLY ESKRKFQNGE VIVLTGANSG IGLATLTELA GRGCHLVIGT RSVTVGQDIR
     DKLLHQHPVA TVDVFELKLE SLASVAEFSE NVRNLGKPLY ALINNAGVFY APPSLTDDKL
     EYLYQVNYLA HFLLTLRLLP ALKQHPADSR IVNVVSQAHR SVTEVSTDDS FLGALFQDTP
     SNRFRAYQYS KFCLVQFSYR LSQLLAVGSS NIPSVHCIDP GNVETAIYRH FPPLANRLFF
     YLQKPLRVLL VKTPHEGAQA LLYAVLSEQK PPFYVRRFWG ERASDFDEIN PLVRKEPLAD
     SLWKRSRQQC SHHLLEMMF
//