ID A0A182N784_9DIPT Unreviewed; 937 AA.
AC A0A182N784;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Bromo domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Anopheles dirus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=7168 {ECO:0000313|EnsemblMetazoa:ADIR003508-PA, ECO:0000313|Proteomes:UP000075884};
RN [1] {ECO:0000313|Proteomes:UP000075884}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WRAIR2 {ECO:0000313|Proteomes:UP000075884};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Walton C., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles dirus WRAIR2.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ADIR003508-PA}
RP IDENTIFICATION.
RC STRAIN=WRAIR2 {ECO:0000313|EnsemblMetazoa:ADIR003508-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR AlphaFoldDB; A0A182N784; -.
DR STRING; 7168.A0A182N784; -.
DR EnsemblMetazoa; ADIR003508-RA; ADIR003508-PA; ADIR003508.
DR VEuPathDB; VectorBase:ADIR003508; -.
DR OrthoDB; 168195at2759; -.
DR Proteomes; UP000075884; Unassembled WGS sequence.
DR CDD; cd05497; Bromo_Brdt_I_like; 1.
DR CDD; cd05498; Bromo_Brdt_II_like; 1.
DR Gene3D; 1.20.1270.220; -; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 2.
DR InterPro; IPR043508; Bromo_Brdt_I.
DR InterPro; IPR043509; Bromo_Brdt_II.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR027353; NET_dom.
DR InterPro; IPR038336; NET_sf.
DR PANTHER; PTHR22880:SF225; BROMODOMAIN-CONTAINING PROTEIN BET-1; 1.
DR PANTHER; PTHR22880; FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS; 1.
DR Pfam; PF17035; BET; 1.
DR Pfam; PF00439; Bromodomain; 2.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 2.
DR SUPFAM; SSF47370; Bromodomain; 2.
DR PROSITE; PS00633; BROMODOMAIN_1; 2.
DR PROSITE; PS50014; BROMODOMAIN_2; 2.
DR PROSITE; PS51525; NET; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 78..150
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 466..538
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 771..853
FT /note="NET"
FT /evidence="ECO:0000259|PROSITE:PS51525"
FT REGION 1..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 171..193
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 369..399
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 422..446
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 558..594
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 619..657
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 687..785
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 851..937
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 422..444
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 767..785
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 857..878
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 903..937
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 937 AA; 98158 MW; D5F57941F81FF88D CRC64;
MQQGSGSNTP TVAPASVPPA VPAAPTIDSM DEPPPRNEPA VEPVNGIVQP LVMPPPDRPG
RLTNQLHFLL RTVMKAVWKH QFSWPFQQPV DAKKLNLPDY HKIIKQPMDL GTIKKRLENN
YYWSSKECIT DFNTMFTNCY VYNKPGEDVV VMAQTLEKLF LTKVSLMPKD ETEMEVQQPK
GGKKKPRTLA PPGTLVGNTS VTGAAAAAGV APNAAIVAGA NAVAVAAAAA AAARARPGSA
LGATVSSSVP PLGGAVPPGM GAASTVTSAV PSVPPIGILP PQTVPGSTNT TTTAGPNASA
VAALTAAAAA AAAASAAAAP HNTMGNPIGG GGAGGGGAPV VNKTPAPANP PYMVNSSQGG
METVLPPQQP AKVKKGVKRK ADTTTPTATV FDPHYGTPMD SSAAKIATRR ESGRQDIVPY
QTSTYPMSPM THQGTTSSQY PPKNKEKLSD ALKSCNEILK ELFSKKHSGY AWPFYKPVDA
ELLGLHDYHD IIKKPMDLGT VKRKMDNREY KSAPEFAADV RLIFTNCYKY NPPDHDVVAM
GRKLQDVFEM RLANIPDEPV NNVAPHHHPG KESEPSSSSE SNDSEDESES DEECAQKLKL
LEKQLFEMQE RMRKLTEEAL QKKKQKKKSK DKKKPSVAGG VGGGGGGSGS GAGDIKPVLD
LHSGLGSMPH GPGKAMHQMA GVMGQVPPMG GGPGAGPPVM PAPGTKAKAK GQRAPKAAAG
GGAVAGGGGG AGGAGPNAPA KRAKNAGGAA GTSAPRAPNK KKASQNVSNF DSEEEDTAKP
MSYDEKRQLS LDINKLPGDK LGRVVHIIQS REPSLRDSNP DEIEIDFETL KPSTLRELES
YVASCLRKKT RKPYYKKVSG KSKEEQMTEK KQELEKRLQD VTGQLGTGKK NAKKDEANKQ
DVAPSGGNMS SSSSSSDSSS SSSSDSSSSD SSDSEAG
//
