ID A0A182NF69_9DIPT Unreviewed; 659 AA.
AC A0A182NF69;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Peptidase S1 domain-containing protein {ECO:0000259|PROSITE:PS50240};
OS Anopheles dirus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=7168 {ECO:0000313|EnsemblMetazoa:ADIR006291-PA, ECO:0000313|Proteomes:UP000075884};
RN [1] {ECO:0000313|Proteomes:UP000075884}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WRAIR2 {ECO:0000313|Proteomes:UP000075884};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Walton C., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles dirus WRAIR2.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ADIR006291-PA}
RP IDENTIFICATION.
RC STRAIN=WRAIR2 {ECO:0000313|EnsemblMetazoa:ADIR006291-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the peptidase S1 family. CLIP subfamily.
CC {ECO:0000256|ARBA:ARBA00024195}.
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DR AlphaFoldDB; A0A182NF69; -.
DR STRING; 7168.A0A182NF69; -.
DR EnsemblMetazoa; ADIR006291-RA; ADIR006291-PA; ADIR006291.
DR VEuPathDB; VectorBase:ADIR006291; -.
DR OrthoDB; 3680196at2759; -.
DR Proteomes; UP000075884; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00190; Tryp_SPc; 2.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 4.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001314; Peptidase_S1A.
DR InterPro; IPR001254; Trypsin_dom.
DR InterPro; IPR018114; TRYPSIN_HIS.
DR PANTHER; PTHR24256:SF537; RE37738P-RELATED; 1.
DR PANTHER; PTHR24256; TRYPTASE-RELATED; 1.
DR Pfam; PF00089; Trypsin; 2.
DR PRINTS; PR00722; CHYMOTRYPSIN.
DR SMART; SM00020; Tryp_SPc; 2.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 2.
DR PROSITE; PS50240; TRYPSIN_DOM; 2.
DR PROSITE; PS00134; TRYPSIN_HIS; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 115..366
FT /note="Peptidase S1"
FT /evidence="ECO:0000259|PROSITE:PS50240"
FT DOMAIN 398..658
FT /note="Peptidase S1"
FT /evidence="ECO:0000259|PROSITE:PS50240"
SQ SEQUENCE 659 AA; 73570 MW; F36424E97E4227AC CRC64;
MNAGTTVNQF NLCYDDELCV DIQKCTLFLP NYNKPAMWSD ALRETFRKRV CQRQENFFGT
VSIHVGSIGR PLFHSQTPPQ TYKVCCGANH IRKYGLELLK LDGCETAIGA RIPRLVRGED
APVDKFPWMV LVFNQRNTSI CTGSLLNEHY VLTLASFKEQ SHSPTHVRLG ELDRNSAIDC
DERGKLCAEP PQDIAIERII PHPDYILLTN NIGLLRLARK ASFNDNVYPI CLPVLSAFHR
IKEPNAPTIQ RRYLVVGWGL NENFKPNNKL KSIKVSVVPN DECQNQFSTD MLVARIIDSH
ICAIGQNMSG TCRGDAGAPM IAMNVNGLYV QYGLLSFGPG SCSYADIPDV YTRVESFVPW
ILDNLEEPPS STHKVCCGAD NIRKHGLELL KLDGCETAIG ARIPRLGRGE DAPVDTFPWM
VMVLTENNHT LCTGSLLNER YVLTAAHCAY SKLPTHVRLG ELDRNSTIDC NERGKLCAEP
PQDIAVEKVT RHNDYRFRVR HNDIALIRLA ETATLNNNVY PICLPVLSAL HRIKDPNAPT
IQRRYLVVGW GLNENDEINN KLKSIKVSVV PNGECQQRLT TYNERAKIFD SHICAIGQNM
SGTCGGDAGA PMIAMNVNGL YVQYGLLSFG PGSCSYADIP DVYTRVESFV PWILDTLEE
//
