ID   A0A182NHX9_9DIPT        Unreviewed;       998 AA.
AC   A0A182NHX9;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:ADIR007252-PA};
OS   Anopheles dirus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=7168 {ECO:0000313|EnsemblMetazoa:ADIR007252-PA, ECO:0000313|Proteomes:UP000075884};
RN   [1] {ECO:0000313|Proteomes:UP000075884}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WRAIR2 {ECO:0000313|Proteomes:UP000075884};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Walton C., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles dirus WRAIR2.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:ADIR007252-PA}
RP   IDENTIFICATION.
RC   STRAIN=WRAIR2 {ECO:0000313|EnsemblMetazoa:ADIR007252-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
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DR   AlphaFoldDB; A0A182NHX9; -.
DR   STRING; 7168.A0A182NHX9; -.
DR   EnsemblMetazoa; ADIR007252-RA; ADIR007252-PA; ADIR007252.
DR   VEuPathDB; VectorBase:ADIR007252; -.
DR   OrthoDB; 3686044at2759; -.
DR   Proteomes; UP000075884; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR   InterPro; IPR048591; Ctf4-like_C.
DR   InterPro; IPR022100; Mcl1_mid.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR19932; WD REPEAT AND HMG-BOX DNA BINDING PROTEIN; 1.
DR   PANTHER; PTHR19932:SF10; WD REPEAT AND HMG-BOX DNA-BINDING PROTEIN 1; 1.
DR   Pfam; PF20946; Ctf4_C; 1.
DR   Pfam; PF12341; Mcl1_mid; 1.
DR   Pfam; PF00400; WD40; 1.
DR   SMART; SM00320; WD40; 4.
DR   SUPFAM; SSF50993; Peptidase/esterase 'gauge' domain; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 1.
PE   4: Predicted;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW   ProRule:PRU00221}.
FT   REPEAT          129..169
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   DOMAIN          412..693
FT                   /note="Minichromosome loss protein Mcl1 middle region"
FT                   /evidence="ECO:0000259|Pfam:PF12341"
FT   DOMAIN          714..775
FT                   /note="DNA polymerase alpha-binding protein Ctf4-like C-
FT                   terminal"
FT                   /evidence="ECO:0000259|Pfam:PF20946"
FT   REGION          339..359
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          816..919
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          953..998
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        834..878
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        885..913
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        968..984
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   998 AA;  109309 MW;  B13DFAF676900620 CRC64;
     MPFKRSPMRY AHIMGYTSIV YQDDGNCIIS VGYDGDFRMW HGIGDDDPPT VCVGEHVYTA
     LQYDGRALVA TDLNTVQAYK YPSLEKDGIE FRFTAFVSCL AKNKRFIVAG SEDATIKVLS
     IDNGEQFELE NLEGPVLSLD VSKHDLLAAS IGDGKLRVWD MKTKELKHTI EGLPKVKTFE
     AAEYFTAPSF EPRSGALLAY PSGRGVVVLN TTSWKEVKTF TNKKLTADLT VCRFSPMGDY
     VAAGSLAGEV AIWDCEKGTL IEGEAPYDLN PITRLVWNPK NNGELAISDA NGQVGTVTNI
     FVDAADDEDG DEGDIMLMAE KEENGENSDD AHDDIFAAHT KRDEKDSDKE ASDDDEDNEN
     CIELEKLKSQ IMGPTQQIDD ALLDDDDDDD DDRGTVRSER TAVLAKSFPQ QEPFQPGSSP
     NTLEHNYLVY NHVGIVRRHV TDKENSIEVE FHDSQQHHGI HLNNFLHHSL AGLSETVLAM
     ACPAQEKNAS KIVCINQAAF GKREWTYTMP SLEEIIAVTA SDKIVVVGTD SRLLRVFTAR
     GTQREVITVA GPIVALAAYG DHFLAAYHSA PASEDQHISL MIVTCVNFKL RCREVRVPLT
     AASQLRWIGF TDRGSPVVYD SAGQMNIYHA SSNIWMPIYH ADNLPSKGAS DGLFIIKVSE
     STQSVQLVLC RGAKYPLTNP IPIPLEVKFS IPMCDMDSEK ECLEDELVRS LYLKVNDADK
     LLKETAVKLF ALSCKNECEQ RAKELVETIA SSQLIPLVIK YASKIRRYHL ADSLAPLLPT
     FQEQEVQEEK LEQESARESA AIVSELQHIN LEAISKKDTT PKIKPLPVGT KKPSNPFRRT
     TTTGSSDGGG GSGGGISSPA SSASGHQNGA NSSNPLEHLT GKAIGFSASR SSSSPTVGQD
     ENRPQNSAGG GSSTPGGMKF LPWFEQRREE LQKRHPGAAD AELIKIGMRE FKAQQQKGVS
     QADGAGTSKA TDKRKLDEVD QPESGVSKLA KFSFAKSS
//