ID   A0A182NP07_9DIPT        Unreviewed;       505 AA.
AC   A0A182NP07;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   03-MAY-2023, entry version 25.
DE   RecName: Full=PAT complex subunit CCDC47 {ECO:0000256|ARBA:ARBA00034875};
DE   AltName: Full=Coiled-coil domain-containing protein 47 {ECO:0000256|ARBA:ARBA00034902};
OS   Anopheles dirus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=7168 {ECO:0000313|EnsemblMetazoa:ADIR009392-PA, ECO:0000313|Proteomes:UP000075884};
RN   [1] {ECO:0000313|Proteomes:UP000075884}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WRAIR2 {ECO:0000313|Proteomes:UP000075884};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Walton C., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles dirus WRAIR2.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:ADIR009392-PA}
RP   IDENTIFICATION.
RC   STRAIN=WRAIR2 {ECO:0000313|EnsemblMetazoa:ADIR009392-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Rough endoplasmic reticulum membrane
CC       {ECO:0000256|ARBA:ARBA00034697}; Single-pass type I membrane protein
CC       {ECO:0000256|ARBA:ARBA00034697}.
CC   -!- SIMILARITY: Belongs to the CCDC47 family.
CC       {ECO:0000256|ARBA:ARBA00034746}.
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DR   AlphaFoldDB; A0A182NP07; -.
DR   STRING; 7168.A0A182NP07; -.
DR   EnsemblMetazoa; ADIR009392-RA; ADIR009392-PA; ADIR009392.
DR   VEuPathDB; VectorBase:ADIR009392; -.
DR   OrthoDB; 5252467at2759; -.
DR   Proteomes; UP000075884; Unassembled WGS sequence.
DR   GO; GO:0030867; C:rough endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0032469; P:endoplasmic reticulum calcium ion homeostasis; IEA:InterPro.
DR   InterPro; IPR012879; CCDC47.
DR   PANTHER; PTHR12883; ADIPOCYTE-SPECIFIC PROTEIN 4-RELATED; 1.
DR   PANTHER; PTHR12883:SF0; PAT COMPLEX SUBUNIT CCDC47; 1.
DR   Pfam; PF07946; CCDC47; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136}; Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..505
FT                   /note="PAT complex subunit CCDC47"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5008130208"
FT   REGION          51..106
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          449..505
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        91..106
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        449..489
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   505 AA;  56846 MW;  D939FBAFC7574A7A CRC64;
     MRLLLPLAAV LALLCLVPQF VVAQGGADNG EDNDFAEFED FDDDEFVMGE THQAGQQPPA
     PAQAGAEARQ GIDPAKGQPK GAGGASPQDS EDFMEIDDDH ADDDGIVEDE DSEFEHFQDE
     EEFEGFAGTI GEQDELREGE PTVGGKHAEP KLTIPKVPIH FRTHWDSYWM EMLMLAGLMA
     YFANYLVGNK KNSAIANQWL SIHRSLLEDN FALVGDDGKK ETEGSTFSFN KESESVYTLW
     CSGRTCCEGM LVELKMIKRQ DLVSLIAGIM KPVQDQLHIK VELSPDSMDN FVFCVASRKQ
     ATKMFKELND LNKFCCLVSK AEDKYGVPGF AVLSEIAEVS SSVLDGRIVA ALNKYSHLID
     YIHLSDQYSG PIQQEDPNQL KRPEVKRILH CGFNVPVKGD LEEMKPLLIL VFYLMDRVRR
     LKLSKEAKAK SDKNRAAVEE EFMKSTHQAR AEAAAVRREE KRKAEKEKIL AEEDPEKQRR
     WEKKEQKRQL KKQAPKMKQL SIKAL
//