ID   A0A182P085_9DIPT        Unreviewed;      1200 AA.
AC   A0A182P085;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=Nucleoporin Nup133/Nup155-like C-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Anopheles epiroticus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=199890 {ECO:0000313|EnsemblMetazoa:AEPI000317-PA, ECO:0000313|Proteomes:UP000075885};
RN   [1] {ECO:0000313|Proteomes:UP000075885}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Epiroticus2 {ECO:0000313|Proteomes:UP000075885};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Howell P., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles epiroticus epiroticus2.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AEPI000317-PA}
RP   IDENTIFICATION.
RC   STRAIN=Epiroticus2 {ECO:0000313|EnsemblMetazoa:AEPI000317-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the nucleoporin Nup133 family.
CC       {ECO:0000256|ARBA:ARBA00005569}.
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DR   AlphaFoldDB; A0A182P085; -.
DR   STRING; 199890.A0A182P085; -.
DR   EnsemblMetazoa; AEPI000317-RA; AEPI000317-PA; AEPI000317.
DR   VEuPathDB; VectorBase:AEPI000317; -.
DR   OrthoDB; 4246256at2759; -.
DR   Proteomes; UP000075885; Unassembled WGS sequence.
DR   GO; GO:0005643; C:nuclear pore; IEA:UniProt.
DR   GO; GO:0017056; F:structural constituent of nuclear pore; IEA:InterPro.
DR   Gene3D; 1.20.58.1380; -; 1.
DR   Gene3D; 1.25.40.700; -; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR007187; Nucleoporin_Nup133/Nup155_C.
DR   InterPro; IPR014908; Nucleoporin_Nup133/Nup155_N.
DR   InterPro; IPR037624; Nup133-like.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR13405; NUCLEAR PORE COMPLEX PROTEIN NUP133; 1.
DR   PANTHER; PTHR13405:SF11; NUCLEAR PORE COMPLEX PROTEIN NUP133; 1.
DR   Pfam; PF03177; Nucleoporin_C; 1.
DR   Pfam; PF08801; Nucleoporin_N; 1.
DR   SUPFAM; SSF117289; Nucleoporin domain; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          67..497
FT                   /note="Nucleoporin Nup133/Nup155-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08801"
FT   DOMAIN          712..1060
FT                   /note="Nucleoporin Nup133/Nup155-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03177"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          444..463
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        9..23
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        444..458
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1200 AA;  136439 MW;  B896FC8A2BA703B0 CRC64;
     MDRTFSFGGG PIKNSTMSRS RQSLGGSLFS GGARSTNTST FARQGSGRYS LSSRSNVSSL
     RVVAKSEYNI LESYGFSLPV QVTEVLTFNE RSINVSVNYG QNGWAWLVQG RRLFVWQYRE
     NPGQKAGSGF GGGEHFSTPR RPYAGQCRQL TLPHCDIGHK ATLVTVFVNE GHQMASCLAV
     SPAGDVRYWQ SIAHDGSSID ECNILEGQEF EQLIGLGGQE FVLATTTCSL MRLNVHLQNG
     RYVIVPRLIK PPSGFFGGIG KRFASIIIGM HSNQERENKL VKISCERISQ NPCEWHITVL
     ADRWIQRWAV QPHNGNERFL SEDADIMKKM RDYFHQKLWN TRDASEIELW ALDMQPTDRG
     VIILSAAVNQ QRSQQVYYAL MTVIFEPDNT FTLRDTTIMR YKGFYSAERL AELIDFRFIA
     NRSFAYVYND RYIFPVALSE TGATGTGHGS NGSSPPASAS GEEVEKIEFH AREDMILMGN
     CFQNTPLFFS RLNGMVIVTP SDFDPSDMFN SSVSSDVFNP NSASFVDTTV LMQQSIFAPA
     TTNAGNLILY DLDPEEIANS TDVPEQDPVH HLKAAFIYHI KRNALAADEL IATVLELAGQ
     RDQVDSELDR TVLKIAIDLA QDTPAADPRW EVTNKHALGS STSMQIIQQL REKNIAFTQF
     IEFLHSRKLW DRLSAVGSTE LGDARPTARC LADVGEKIVA AIGIKCLHNS HSRIIDEAIN
     LVLRQSNRTI PFPNLTPQDL FYAQTHRVEE LFRVLSELVD GYVQQELSAL QIQTALVEVN
     TIVLTVLQEV LKYREAKATM YTVRDELQNR YEQTPWTAMS GRNGMRDVLL QLISCTLRHG
     VKGTAEPEFR MKHFKHLTEL IDYVLDGRKT YLESVHDEEK YTVLLQQYES QRSDLIYPLV
     EAEQYEMAAK LAEKYLDFQT LVQICDKTNN QERLDEYIER YKEYDFSQFA ISWHMHQNKQ
     GDILHRFKNN QSALARFLVD HPSMAWIQLL FNGELSQAAE VLLSLAQREK ELLARKRAML
     CLGKLCLLAA EGDTFQTQID NINAELELID IQENIPSEIL DMFGYDTKHV KVLAPEEIVD
     LYIADEYSKS SEKEFRYALS LLPFVEDPIE VRHRIWCAAI QRDSWEEYNK NAPLDSMQNM
     LFFRLIDLCY ISDAGELENF LPPLESFLNA PELGDLTQSK SFQYLMKLGY EHINESYRKK
//