ID A0A182P1B7_9DIPT Unreviewed; 594 AA.
AC A0A182P1B7;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
OS Anopheles epiroticus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=199890 {ECO:0000313|EnsemblMetazoa:AEPI000699-PA, ECO:0000313|Proteomes:UP000075885};
RN [1] {ECO:0000313|Proteomes:UP000075885}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Epiroticus2 {ECO:0000313|Proteomes:UP000075885};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Howell P., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles epiroticus epiroticus2.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AEPI000699-PA}
RP IDENTIFICATION.
RC STRAIN=Epiroticus2 {ECO:0000313|EnsemblMetazoa:AEPI000699-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
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DR AlphaFoldDB; A0A182P1B7; -.
DR STRING; 199890.A0A182P1B7; -.
DR EnsemblMetazoa; AEPI000699-RA; AEPI000699-PA; AEPI000699.
DR VEuPathDB; VectorBase:AEPI000699; -.
DR OrthoDB; 3412018at2759; -.
DR Proteomes; UP000075885; Unassembled WGS sequence.
DR GO; GO:0052689; F:carboxylic ester hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002018; CarbesteraseB.
DR InterPro; IPR019826; Carboxylesterase_B_AS.
DR PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR PANTHER; PTHR11559:SF370; CARBOXYLIC ESTER HYDROLASE-RELATED; 1.
DR Pfam; PF00135; COesterase; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Serine esterase {ECO:0000256|ARBA:ARBA00022487}.
FT DOMAIN 121..562
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 594 AA; 67858 MW; 3C476AAB74E17694 CRC64;
MVAMEAKEGR HQKPDRNRIW RQRQSSGSGA GSEFSDKIFT RNRLSPAESG PTDHVAMWLC
AAVFIGHLFI GSSVQASCLV RYDRSATGTG ILRRTFYRLP YCAYYGHSVL YQPSGNETYD
TPGSMCAQYN NPFARDYVIG SEDCLFANIY KPHVAGQETP RPVLVYVHGG SYISGHGEND
INGADLLLDI GVVVVTFNYR LNVLGFLKSN EFNISGNFGL KDQTTLLRWV QRNIRSFGGD
PDQVTLLGQS AGAGSATHHL YIPQSKDLFH RMIVLSGSLL APWSFLYKPQ PCMERYLSEL
NLTTASELRT KPLDELLVPN ATHQYSFQFA SMESPCFIPV LEQEEIHHDN FTVNPPHQSV
LGPPVTSVPI LLSETAREFE NQLQDISDFL LFPNLPQSWD ALKGQKWNDS MELFIRNVVE
QGDAKSREEV LQQIAIIANM RYPMRRLALH LADSLKQSAP VYFARFEFDG KFGRAKHLVY
RSYLPESTYG AMHGDDLGYI FSPYNLEKAI TDWNQYRLEW RIHISMGLLL EKFINHGHIV
YDGKPLNSLA TANTYLNIDK TFEVREFQDS RIFRHWAEMY NCLYYETCEY KWCW
//
