ID A0A182P7C9_9DIPT Unreviewed; 1512 AA.
AC A0A182P7C9;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=SEA domain-containing protein {ECO:0000259|PROSITE:PS50024};
OS Anopheles epiroticus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=199890 {ECO:0000313|EnsemblMetazoa:AEPI002831-PA, ECO:0000313|Proteomes:UP000075885};
RN [1] {ECO:0000313|Proteomes:UP000075885}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Epiroticus2 {ECO:0000313|Proteomes:UP000075885};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Howell P., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles epiroticus epiroticus2.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AEPI002831-PA}
RP IDENTIFICATION.
RC STRAIN=Epiroticus2 {ECO:0000313|EnsemblMetazoa:AEPI002831-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR STRING; 199890.A0A182P7C9; -.
DR EnsemblMetazoa; AEPI002831-RA; AEPI002831-PA; AEPI002831.
DR VEuPathDB; VectorBase:AEPI002831; -.
DR OrthoDB; 3038066at2759; -.
DR Proteomes; UP000075885; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.960; SEA domain; 1.
DR InterPro; IPR000082; SEA_dom.
DR InterPro; IPR036364; SEA_dom_sf.
DR Pfam; PF01390; SEA; 1.
DR SUPFAM; SSF82671; SEA domain; 1.
DR PROSITE; PS50024; SEA; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1337..1361
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1155..1283
FT /note="SEA"
FT /evidence="ECO:0000259|PROSITE:PS50024"
FT REGION 1..219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 261..283
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 437..458
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 486..586
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 598..654
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 948..1002
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1068..1098
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1122..1151
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1255..1286
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..77
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 78..92
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 102..219
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 546..586
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 614..630
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 631..649
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1122..1149
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1512 AA; 164281 MW; 19568F7A08840AB1 CRC64;
TPRSADIFEI SPRPFSATPS SNAGFQYSRS PPRSDFFSNG LTASRSFPAS NRQLAGSSQR
KSPFSSSSAG FPQLATTETP QRPPPAAPAP SSPAEPASVR DRQLSYISSR ARPFASEDQQ
QQQQPPTRAS TYQQSRQPLP RSPSSTSSGT RNSFSSSRSK PTDSSNVGRS QTGTASTQNG
TANGRFGGTQ SSRTTARPNR YRSIPTTTTT TEAATERTTT VDSVAVRNRF SGRTPAPNPF
RQAFEAKRVP TVNSAIATRG SFPSAAKPKT TTTTTTTTTT TTTTTTTAKV PVLSRFIHQP
AKPIIPSINI THNGSAKSAE VIYDYDDYEE SKESTGFDGE KQQEINDFQP TPQAKNNSIV
LTSAVQEPQL VPGTGSLASA GVPGAAGTTK TLLEDPDGRL NNISENEYYD TVREPETAPG
DSVGVEDHTV ILTDNFYLPN GGSEETFEED DEEPEGGQRE INSTAEQLGA EQQEKLYDDE
YVYEDEEPIT TTVRPTVKAV AAPPSATEQL DDDAADMLQF SDEDLKDDPA GKLPPAAGGT
KETLPEASTA APTVRTESTT ETSLSTTERV ASSSEAEAGT NATTESWVVV ASVQTSRSVS
GARFLPFPQV EQEEKKQPLA ELESKGSNES DDGEVTTASG VSDDSEGPTT IAPQEPVIAV
TDVVDSVTTE KTLIVQSTES IIDKLDRVQS ELSSGLFAGK FPVLKDPAAE DQKTASSTAL
PPVVIRKFQP NARATTTKKP RPGLTTTVKP ATTATTDSLV KKIKFETIDD ISALLPPDYK
AKAGFKLKKP NPAGETVPAT NEAPLEDAAK PELGNRFRSA NISRSYKSNV PIQELSSLLP
KDYKLNRTEE DIKNTNNLKE LISKVKVNDK PNPALDLLKK AQKVDVSAFL PPGYKPTEAS
PSTTVKVLPV SVEDDVSKFL PPGYKTFKTT KKPTAPVPVT IRDDVSKLLP PGYKLPKEPD
STSERPKVVF NEDVSKLLPP GYKPPADEDT KPEPEAIDPS SLLKKIQFKD VSALLPPGFN
ASKAEEPSST VATGSAAGSG FKVVFPSRPG AKKPLPGTAA RATTAKPLHA EGPGVPEIHI
RKGPPTRATT EFTGWPTPST TPLSIEKLLE QQKQQELLEK LLASSSSTST TTTTTTTTTT
TTTTPRPTEP GLCHSECDLA GTIRIVDGVK WVPELLDHNT AEWKKLAREV ETELNEVYSK
AKNLSKWYKK VRIDSFNKGS VLVDYFVELT DLSRDINTLE IRKMFHEALV PVPETTTLPT
TTSTRSSSSE DDYDGEREDG ETKAEKENLQ VPAHRVKEVF QLGKFRVDPV YTDFTVIPKP
ILAAGPAIED DLFLPQWAIA VIVIGLASLL FVILFGVTVL INRQKAAKKK APTPLTADML
NELNKNHMGG IENFGSEDLY NLDDAWDDRM HDVKPKRFSN SMHGSSASNI YDSWRSQRHP
ENYFYDDYGL KGSHYPPSGH HHRLHDPAFM MHEPPPPVMA MYPPYHHAPP PPNSHHFSNS
SRRYYRDYDP NF
//
