ID   A0A182P8T9_9DIPT        Unreviewed;       531 AA.
AC   A0A182P8T9;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=PHD-type domain-containing protein {ECO:0000259|PROSITE:PS50016};
OS   Anopheles epiroticus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=199890 {ECO:0000313|EnsemblMetazoa:AEPI003343-PA, ECO:0000313|Proteomes:UP000075885};
RN   [1] {ECO:0000313|Proteomes:UP000075885}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Epiroticus2 {ECO:0000313|Proteomes:UP000075885};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Howell P., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles epiroticus epiroticus2.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AEPI003343-PA}
RP   IDENTIFICATION.
RC   STRAIN=Epiroticus2 {ECO:0000313|EnsemblMetazoa:AEPI003343-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   AlphaFoldDB; A0A182P8T9; -.
DR   STRING; 199890.A0A182P8T9; -.
DR   EnsemblMetazoa; AEPI003343-RA; AEPI003343-PA; AEPI003343.
DR   VEuPathDB; VectorBase:AEPI003343; -.
DR   OrthoDB; 5490909at2759; -.
DR   Proteomes; UP000075885; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd15619; PHD1_d4; 1.
DR   CDD; cd15530; PHD2_d4; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR025750; DPF1-3_N.
DR   InterPro; IPR011011; Znf_FYVE_PHD.
DR   InterPro; IPR001965; Znf_PHD.
DR   InterPro; IPR019787; Znf_PHD-finger.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR45888; HL01030P-RELATED; 1.
DR   PANTHER; PTHR45888:SF13; ZINC FINGER PROTEIN UBI-D4; 1.
DR   Pfam; PF14051; DPF1-3_N; 1.
DR   Pfam; PF00628; PHD; 2.
DR   SMART; SM00249; PHD; 2.
DR   SUPFAM; SSF57903; FYVE/PHD zinc finger; 2.
DR   PROSITE; PS50016; ZF_PHD_2; 2.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00146}.
FT   DOMAIN          419..479
FT                   /note="PHD-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50016"
FT   DOMAIN          476..526
FT                   /note="PHD-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50016"
FT   REGION          106..367
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        150..165
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        166..197
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        285..306
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        342..358
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   531 AA;  55735 MW;  F268BBD3282E87CC CRC64;
     MASSDLIVNV NNLEKIENFF NDSTYKEIIE NSETFNTRLC LERRLRMPFL DPQTGVAQNH
     CALFMHSRHR IPGLKNGQVY SYPAARWRKS RRQYLLQKPH PPFPAYTHRP FGHLQPAPAS
     SLGMPGSGLG SDRGGGGGGG GGGGGGGGGS TYDSENSNLD QSSAVDASDL KEHESEKAGK
     DWYYDEMEMH DMESFEDHDL PDSDCDYEES FSQRKKKSKS GRSGGGGGGG GSGGGRSKSG
     GSSLSEANNR RGGRGGGRGR GRKSQGIGGE LGPSFKDMVE TPKKNRVQTL PNLTPQSNSS
     SPLTLPGGGS GGAGGPEELP LVPELAPEVK VDGGGDPTDG SGAPKLSNSN NRSGLGPPNH
     AAPNNVPGGP IAALAGAAAA VGGGAPVSTI VPPGPGVVGG PGGPGVGGVP GEKSRAIPSP
     YCDFCLGDAR ENKKTFEPEE LVSCSDCGRS GHPSCLQFTA NMIISVRKYR WQCIECKYCT
     ICGTSDNDDQ LLFCDDCDRG YHMYCLSPPL VSPPEGSWSC KLCKEEFHKP K
//