ID A0A182P9D9_9DIPT Unreviewed; 725 AA.
AC A0A182P9D9;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=K Homology domain-containing protein {ECO:0000259|SMART:SM00322};
OS Anopheles epiroticus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=199890 {ECO:0000313|EnsemblMetazoa:AEPI003544-PA, ECO:0000313|Proteomes:UP000075885};
RN [1] {ECO:0000313|Proteomes:UP000075885}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Epiroticus2 {ECO:0000313|Proteomes:UP000075885};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Howell P., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles epiroticus epiroticus2.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AEPI003544-PA}
RP IDENTIFICATION.
RC STRAIN=Epiroticus2 {ECO:0000313|EnsemblMetazoa:AEPI003544-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR AlphaFoldDB; A0A182P9D9; -.
DR STRING; 199890.A0A182P9D9; -.
DR EnsemblMetazoa; AEPI003544-RA; AEPI003544-PA; AEPI003544.
DR VEuPathDB; VectorBase:AEPI003544; -.
DR OrthoDB; 1662at2759; -.
DR Proteomes; UP000075885; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd22397; KH-I_FUBP_rpt2; 1.
DR CDD; cd22398; KH-I_FUBP_rpt3; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 3.
DR InterPro; IPR015096; FUBP_C.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR PANTHER; PTHR10288; KH DOMAIN CONTAINING RNA BINDING PROTEIN; 1.
DR PANTHER; PTHR10288:SF171; P-ELEMENT SOMATIC INHIBITOR, ISOFORM C; 1.
DR Pfam; PF09005; DUF1897; 2.
DR Pfam; PF00013; KH_1; 3.
DR SMART; SM00322; KH; 3.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 3.
DR PROSITE; PS50084; KH_TYPE_1; 3.
PE 4: Predicted;
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117}.
FT DOMAIN 168..239
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 252..323
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 375..447
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT REGION 1..169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 329..364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 404..424
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 466..510
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 635..725
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 47..61
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..83
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 93..114
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 494..510
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 725 AA; 73778 MW; 7C87052CC14FCD01 CRC64;
MSDYSNQNSQ NFSQSSAFAA ALQRAKQIAA KIHPGGHQQQ QQPHQPVKRP LDDHDSGPEL
KKFGGQPDYN NASSPTGMSQ AAMQAAAQAA AVAARLSQNN SSNNQNNFNS PNAPPGGGGP
QDPNQRVREL ISKMVNHGPM DNGNHPGQGG GGGGGGGRGG GGGGGGGFAT FQEMMIPGSK
VGLIIGKGGE TIKQLQEKTG AKMVIIQDGP TQEMEKPLRI SGDPQKVEQA KQLVYELIQE
KDAYSQRQNM NGAEQAEVFV PKAAVGVVIG KGGEMIKKIQ GESGCKLQFI QGRGDGAGDR
RCIVQGSKAQ VEEGKRMVED LIDSVLRREQ QGGGRGGGGG GGGGGGDGGH GGRGGMGGNA
NQDNNYNNYN GPQVMRLEYT FTVPVSKCGI IIGRGGDTIK QINQQSGAHT EMDRKASQNQ
TTEKTFTCKG EQHQVDEAKR LIQDKINMEI NMVYVGSSSV PVNQYQNNGA GGGGGGGGGG
GGGGGGGGPY QQGGWGGYQS QGGWEQQQSA QVNAASAAAA AAAAAAQQQQ QPQADYSQQW
IEYYKQMGML REAEVIEQQI KARQASQGTM AVMAAAGAGA PQQQAQQQQQ AGGQADYSAE
WAEYYRRIGK IDEAEAIEKQ IAANKAVAAA AAAAAGGNQP GGPGGAGAGQ YGGGGGGPQQ
PGPGGYGGQQ YQQYYGGGGG GGGAGGAGGG GGQPGYAGYP YGGGYPGPGG GGAPNQPNAP
NQDKN
//
