ID   A0A182PC86_9DIPT        Unreviewed;       653 AA.
AC   A0A182PC86;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Lipase domain-containing protein {ECO:0000259|Pfam:PF00151};
OS   Anopheles epiroticus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=199890 {ECO:0000313|EnsemblMetazoa:AEPI004541-PA, ECO:0000313|Proteomes:UP000075885};
RN   [1] {ECO:0000313|Proteomes:UP000075885}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Epiroticus2 {ECO:0000313|Proteomes:UP000075885};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Howell P., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles epiroticus epiroticus2.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AEPI004541-PA}
RP   IDENTIFICATION.
RC   STRAIN=Epiroticus2 {ECO:0000313|EnsemblMetazoa:AEPI004541-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the AB hydrolase superfamily. Lipase family.
CC       {ECO:0000256|ARBA:ARBA00010701, ECO:0000256|RuleBase:RU004262}.
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DR   AlphaFoldDB; A0A182PC86; -.
DR   STRING; 199890.A0A182PC86; -.
DR   EnsemblMetazoa; AEPI004541-RA; AEPI004541-PA; AEPI004541.
DR   VEuPathDB; VectorBase:AEPI004541; -.
DR   OrthoDB; 5398733at2759; -.
DR   Proteomes; UP000075885; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0016298; F:lipase activity; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   CDD; cd00707; Pancreat_lipase_like; 2.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 2.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR013818; Lipase.
DR   InterPro; IPR033906; Lipase_N.
DR   InterPro; IPR000734; TAG_lipase.
DR   PANTHER; PTHR11610:SF150; FI01825P-RELATED; 1.
DR   PANTHER; PTHR11610; LIPASE; 1.
DR   Pfam; PF00151; Lipase; 2.
DR   PRINTS; PR00821; TAGLIPASE.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 2.
PE   3: Inferred from homology;
KW   Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..29
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           30..653
FT                   /note="Lipase domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5008131232"
FT   DOMAIN          47..295
FT                   /note="Lipase"
FT                   /evidence="ECO:0000259|Pfam:PF00151"
FT   DOMAIN          374..649
FT                   /note="Lipase"
FT                   /evidence="ECO:0000259|Pfam:PF00151"
SQ   SEQUENCE   653 AA;  71418 MW;  5DA820345D54EA41 CRC64;
     MLPSGWKWSA EVFVVLMVIG EFPLHLAEAG DSDLNEVRIG FGSSFSAKRD VRFHLYTPLN
     RADAHVFAID TVDTLMRSFY NSSHPVRIII HGWFNNATSL VIQGVKDAYL EAGSYNVIGV
     DWGVGAGESY FRASQYTIAV GLVVADLIKQ LVRSGMVEME RLYVVGHSLG AHIAGNAGHA
     LKTQPLHVIY GLDPASINFF QDEPDSRLSP DDAIYVEVIH TNTQLSGYPA PLGHVDFYMN
     YGRKQPGCKT DVCSHGRSTE YFIESLGIAT KGFWGVGCND YSEIRQRTCY NIKQQALMGG
     EYWQKNITAG VYTVETLSET PYAMASAGTL SSRNNDNNEW HIAADENGLM RLVSYTAPYQ
     LDGERPRVDF VPERDTRFLL YTASNPEVPH VLRNGDLDSI INSPFNANYP TRMVIHGWLG
     TQNSEINRLT RSALFFGGNY NVIYVDWSVG ALDEFYPNSR QLVYAVAAAA SNMLDYLARY
     TGLNKRDVVV VGHSLGAHVA GNVGKWQSGA IGTIIGLDPA LPFFAGDVPD RIMASDADYV
     EIIHTNGGVL GFMDPIGDAD FYPNFGRIQP GCGVDVGGGC AHARAVHFYV ESILSRNGFV
     GQQCESFQNI RDGTCAQTGV TSRMGGEPPN ADGAPTGIFF LQTANSFPFA VGC
//