ID A0A182PEH7_9DIPT Unreviewed; 887 AA.
AC A0A182PEH7;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=AMP-dependent synthetase/ligase domain-containing protein {ECO:0000259|Pfam:PF00501};
OS Anopheles epiroticus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=199890 {ECO:0000313|EnsemblMetazoa:AEPI005332-PA, ECO:0000313|Proteomes:UP000075885};
RN [1] {ECO:0000313|Proteomes:UP000075885}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Epiroticus2 {ECO:0000313|Proteomes:UP000075885};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Howell P., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles epiroticus epiroticus2.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AEPI005332-PA}
RP IDENTIFICATION.
RC STRAIN=Epiroticus2 {ECO:0000313|EnsemblMetazoa:AEPI005332-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR AlphaFoldDB; A0A182PEH7; -.
DR STRING; 199890.A0A182PEH7; -.
DR EnsemblMetazoa; AEPI005332-RA; AEPI005332-PA; AEPI005332.
DR VEuPathDB; VectorBase:AEPI005332; -.
DR OrthoDB; 3305653at2759; -.
DR Proteomes; UP000075885; Unassembled WGS sequence.
DR CDD; cd05930; A_NRPS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.630.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR44845:SF6; BETA-ALANINE-ACTIVATING ENZYME; 1.
DR PANTHER; PTHR44845; CARRIER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450}.
FT DOMAIN 26..409
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
SQ SEQUENCE 887 AA; 99476 MW; 57C1DE61A70CD9A2 CRC64;
MGTLPQLAVV KGKLCPLQPT LLHRTFEANV DKFCGTDTAL IYNDEARGEV QRNYNELNST
ANRLATAMLN RIKDHFRSQP NTDGDYIVAV CLHPTDRLVT TLLAIWKAGA AYLPIDPTFP
PNRIQHILGE AKPALVVYDD DYDNAAIFGK TPAISYAELR KRASDLSNAN IRPEAMLGKG
DSQLALVLYT SGSTGVPKGV RLNHETILNR LQWQWSRFPY SPTERIGVFK TALTFVDSVS
EIWGPLLNGM AIVVVPKKIT NNPEKLVEVL ERYRIERLVL VPTLLRSLLL YLPLQQHQQP
RSGSKLLYNL RVWVCSGEPL QISLAREFFD YFQEGVHQLC NFYGSTEVMG DVTYFVCESR
KQLESYEKVP IGYPLDNTTI YIMSPDLRPV RTEEIGELYV AGLNLAEGYV NGRDPDRFID
NPLAIDPSFG RLYKTGDYAS VSKGCVYYQG RMDSQIKIRG HRVDLSEVEA NLLGLAGIDK
GIVLCYHAGE IDQALLGFVT LEKDSHFQTG LQVEAALGDK LAHYMIPQVV LLESIPLLSL
SNNCNSVFVF HPLPLDDTQI EIEYDYTDVP ANRMTAAKDL FETVGQVIGR STRAKICLAS
NFYELGGNSL NSIITVTQLC GKGYPISITT FIGAKNMGEI LDKICADEQE LAKHQLGTNG
NGNAEGDFDY RMQLTAHPLA FEHKTDTINI ITSSFFEKAD LEQWLKPQIH ETDYRDILED
IWTVLIEKGL SFIVKDETGR PVGVSLNFDA HDEPEVTVTS KLIIVFEFLE FVEGPIRDSQ
LPTGKNQILH SFMMGTCAEL SAQENIEAMH FMENEVLKLA RRRNFAGIFT TNTNPLTQQL
GSNVYNYKTM LDYQVNQFVY SADGTRPFAA APDNQRAVVH WKDIRSS
//
