ID   A0A182PS29_9DIPT        Unreviewed;       884 AA.
AC   A0A182PS29;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=BEACH domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Anopheles epiroticus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=199890 {ECO:0000313|EnsemblMetazoa:AEPI009764-PA, ECO:0000313|Proteomes:UP000075885};
RN   [1] {ECO:0000313|Proteomes:UP000075885}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Epiroticus2 {ECO:0000313|Proteomes:UP000075885};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Howell P., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles epiroticus epiroticus2.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AEPI009764-PA}
RP   IDENTIFICATION.
RC   STRAIN=Epiroticus2 {ECO:0000313|EnsemblMetazoa:AEPI009764-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
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DR   AlphaFoldDB; A0A182PS29; -.
DR   STRING; 199890.A0A182PS29; -.
DR   EnsemblMetazoa; AEPI009764-RA; AEPI009764-PA; AEPI009764.
DR   VEuPathDB; VectorBase:AEPI009764; -.
DR   OrthoDB; 5478899at2759; -.
DR   Proteomes; UP000075885; Unassembled WGS sequence.
DR   CDD; cd06071; Beach; 1.
DR   CDD; cd01201; PH_BEACH; 1.
DR   Gene3D; 1.10.1540.10; BEACH domain; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR   InterPro; IPR000409; BEACH_dom.
DR   InterPro; IPR036372; BEACH_dom_sf.
DR   InterPro; IPR046851; NBCH_WD40.
DR   InterPro; IPR023362; PH-BEACH_dom.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR13743:SF112; BEACH DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR13743; BEIGE/BEACH-RELATED; 1.
DR   Pfam; PF02138; Beach; 1.
DR   Pfam; PF20426; NBCH_WD40; 1.
DR   Pfam; PF14844; PH_BEACH; 1.
DR   SMART; SM01026; Beach; 1.
DR   SMART; SM00320; WD40; 3.
DR   SUPFAM; SSF81837; BEACH domain; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS50197; BEACH; 1.
DR   PROSITE; PS51783; PH_BEACH; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 2.
PE   4: Predicted;
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT   DOMAIN          74..171
FT                   /note="BEACH-type PH"
FT                   /evidence="ECO:0000259|PROSITE:PS51783"
FT   DOMAIN          184..476
FT                   /note="BEACH"
FT                   /evidence="ECO:0000259|PROSITE:PS50197"
FT   REPEAT          626..667
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          709..750
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REGION          1..38
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        18..37
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   884 AA;  98935 MW;  FCBF4141D98DAACF CRC64;
     MRLKLEPDLY HDPHTAAANM RDNTTSTSQS RRLSSEFGST FAPAAIGEEN TDEEMLLLEE
     EMRNSMEPQV PETSGREKIV ISQECELITL MTRVKGRFDL TTSQIMFTEI ASLKDDGQRH
     DFKFPIGQLR ELHLRKFNLR RSALEMFLTD QTSYFLNFTT RTRNKIFTKI LSLQPPNILY
     GSGRSPAELL KSSGLTQKWA NREISNFEYL MHLNTIAGRS YNDLSQYPVF PWILADYTSE
     VLDLNDPKSF RDLSKPIGVV NPKNESEVRN KFDGFEDPSG MIPKFHYGTH YSNSAGVLHY
     LIRVEPFTSL HIELQSGRFD VADRQFHSIP QTWKLLMDNP NDVKELIPEF FYFPEFLKNM
     NRFDLGVLQM TKEKVDDVVL PSWAKTAENF IAIHRRALES EYVSQHLHHW IDLIFGYKQK
     GPKAVESLNV FYYCSYEGAV DLDKIANPVE REAVEGMINN FGQTPSQLLR DPHPRRLSLD
     ELTIRLLKLE LRRPDLTLIL DRVHCTACDL STDKDPVVYV STPKSPPRSF LQTSPDMLIT
     VTKSGILGCH SWMSFDKERG FLLEIDATTL NLKNRKKLTG PFHPSVTLNS KLFAVSVDAK
     YIYAGGIWDN SVRVFNMARG KVVASAINHF DVVTCIAMDN CGSYLVTGSK DCTCVIWSLS
     TSNTVSQPTG SNLQPNTAAL NQNLAGNVVG SANVVHLTNN LTPKPVHTLY GHDDAVSCVA
     IMTELDMVVS GSLDGTVNVH TIKNGQFIRT INPIGCTGCK IEISFITLSY QGHIAFSALD
     DTSHSVHVFS INGVSLGSKY VSGRVTGLTS SSDYLVVADD AGDVTMSRLY GLKPIFDIPL
     HVPTQTVVGT VGNTHLLAPL RDGSLGVIGI QQPIAYKKHT VLNV
//