ID A0A182PW63_9DIPT Unreviewed; 919 AA.
AC A0A182PW63;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Myelin transcription factor 1 domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Anopheles epiroticus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=199890 {ECO:0000313|EnsemblMetazoa:AEPI011200-PA, ECO:0000313|Proteomes:UP000075885};
RN [1] {ECO:0000313|Proteomes:UP000075885}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Epiroticus2 {ECO:0000313|Proteomes:UP000075885};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Howell P., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles epiroticus epiroticus2.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AEPI011200-PA}
RP IDENTIFICATION.
RC STRAIN=Epiroticus2 {ECO:0000313|EnsemblMetazoa:AEPI011200-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the MYT1 family.
CC {ECO:0000256|ARBA:ARBA00010194}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A182PW63; -.
DR STRING; 199890.A0A182PW63; -.
DR EnsemblMetazoa; AEPI011200-RA; AEPI011200-PA; AEPI011200.
DR VEuPathDB; VectorBase:AEPI011200; -.
DR OrthoDB; 3091993at2759; -.
DR Proteomes; UP000075885; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 4.10.320.30; -; 3.
DR InterPro; IPR002515; Znf_C2H2C.
DR InterPro; IPR036060; Znf_C2H2C_sf.
DR PANTHER; PTHR10816:SF15; MYELIN TRANSCRIPTION FACTOR 1-LIKE; 1.
DR PANTHER; PTHR10816; MYELIN TRANSCRIPTION FACTOR 1-RELATED; 1.
DR Pfam; PF01530; zf-C2HC; 3.
DR SUPFAM; SSF103637; CCHHC domain; 3.
DR PROSITE; PS51802; ZF_CCHHC; 3.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT REGION 144..234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 405..545
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 633..652
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 659..703
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 780..863
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 176..205
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 209..233
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 453..513
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 634..649
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 785..839
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 919 AA; 96865 MW; CC8011173957D481 CRC64;
MITLAERNEL GLMDLLLIKS SKCPTPGCVG LGHVTGLYSH HRSLSGCPRR DKVSSELLAL
HETILKCPTP GCNGRGHVSA GRNSHRSLSG CPKAAASKAA ARELKYQNGL LFRQKLHTAV
LNYQQLGEYH SALSAVPVGE VAAREVSPAP RSQQTKAHEA ARAIPADPSG NDGRLVKDLS
SKRVESDIES RDSNAEPEPE PVIKTEQQDD SPIGESSSSA SSTSSSNKML ESSYGRDQDL
ARYGQIGDTR QHQQYTTAHY DANQTLPVST PYELSSYTSR GYDTGAFERY DTTGYGMQKS
FMYGSVYQPV QSSLDEYSVA TAGVATAPPV GNVGTPVQQD TMLPPSGPPL LKVEMPDDSS
SSTEPIYPRP VYHYEPGCAG SPAHPPGYSA INLSVKVTSS EGALRAVGSP GATPTNGTGE
RPPAVDLSSN GVSSSNGGQL AVDGGKGDAD TQLSPKPGTS PNHIKANSPH IPSPQGHTLD
LSVSRLPNSS STSPQYHQDA SAASVTNARS PPTEPVDFSG PPRPLSFGFM GPPGPGYSRE
STPDSGASHY LDGYRDHTGY SPHPGYGMVE YANGYPAYGS NYQACPPYGA SLGPYSSVPG
AGYTSTGSCY AMPPPSHIPS HDKLLKDGLS GLSRTDRQYH SNTQELKCPT PGCDGSGHAT
GNYSSHRSLS GCPRATKPKS KPRDGQESEP LRASGCPIAN RNRMRVMDTG VPSSADLQPQ
HSAKLGSMKF DGVSASNGCD ALNSSHGQGI KKAKYSDEHL SDGVYGKSFS AMSDMVIAHS
PDQDARNGPN PTNLPNGPSQ GALSPSSSMS LSHLRSGTNG GVLSRIQDPS AQQQERPIEQ
RPDVTAGVGG SESGGAGGSS GAGEDLLSLE AEISELQREN ARVESQMLRL KTDITAMETQ
LSHAERVRKL RLVETSLIR
//
