ID   A0A182Q1M9_9DIPT        Unreviewed;       863 AA.
AC   A0A182Q1M9;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=F5/8 type C domain-containing protein {ECO:0000259|PROSITE:PS50022};
OS   Anopheles farauti.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=69004 {ECO:0000313|EnsemblMetazoa:AFAF001303-PA, ECO:0000313|Proteomes:UP000075886};
RN   [1] {ECO:0000313|Proteomes:UP000075886}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FAR1 {ECO:0000313|Proteomes:UP000075886};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles farauti FAR1 (V2).";
RL   Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AFAF001303-PA}
RP   IDENTIFICATION.
RC   STRAIN=FAR1 {ECO:0000313|EnsemblMetazoa:AFAF001303-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
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DR   EMBL; AXCN02001915; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A182Q1M9; -.
DR   STRING; 69004.A0A182Q1M9; -.
DR   EnsemblMetazoa; AFAF001303-RA; AFAF001303-PA; AFAF001303.
DR   VEuPathDB; VectorBase:AFAF001303; -.
DR   OrthoDB; 2714048at2759; -.
DR   Proteomes; UP000075886; Unassembled WGS sequence.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR   InterPro; IPR000421; FA58C.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR006594; LisH.
DR   InterPro; IPR010565; Muskelin_N.
DR   PANTHER; PTHR15526; MUSKELIN; 1.
DR   PANTHER; PTHR15526:SF5; MUSKELIN; 1.
DR   Pfam; PF13415; Kelch_3; 1.
DR   Pfam; PF06588; Muskelin_N; 1.
DR   SMART; SM00667; LisH; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR   SUPFAM; SSF117281; Kelch motif; 1.
DR   PROSITE; PS50022; FA58C_3; 1.
DR   PROSITE; PS50896; LISH; 1.
PE   4: Predicted;
KW   Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          1..66
FT                   /note="F5/8 type C"
FT                   /evidence="ECO:0000259|PROSITE:PS50022"
FT   REGION          27..46
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          731..767
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          792..819
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        743..767
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        799..819
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   863 AA;  98391 MW;  C140D08DB953F008 CRC64;
     MAGTISEIKK LDYDIYKYSS YSSSYLPENI REDNPSNQTS RWSSNTNTPP QYLILKLDRP
     AIVTKIKFGK YEKTHVCNLR KLKILGGLEE GHMVLLFEGG LQNDSVPETF NLKHRTNSGE
     LLPIKYVQIV PLLSWGPSFN FCIWYVELLG IEDSMFILSN LRKYNMLREV EIVRLFMKHC
     RQQGYAKSFS ALQEETGVRL EDEKMTELHE TLVDRGDFKK TEEMLMEFID SGLMDNYLES
     QEYKPQWSLQ LTPENEPRPG RRGGHQLIID QMTSTIYLYG GWDGNEDLSD LWSYDVKANR
     WTLIHERSEL LPDGPTPRAC HKMVYDTKNS VIFMLGRYLD SASRTEENIN SDFYLYNTIH
     KTWCLICNDT SQIGGPQLVF DHQMCIDVDK QTIYVFGGRI LEPKNEEETT GQYRYSGLFS
     YHISTNTWTH ILVDCEHPTA SSPHVLSIRS RVTHSMLFHH KHRKLYIFGG QRGKDYMTDF
     LIYDVDTNEL SNMSPENNNT DTKNVPQSGF TQRATIDCEK DEIYVLTSLS KEKERRDLNI
     NSFWLFSLSK KEWCCVYKSE HSNGENCYQK SQNACHEPCP RYAHQIVYDS TNQVHFLFGG
     NPGTNSNVRL DDFWVLRLEK PNRGNILRYC KYLLRKQEYE EITKNDPHSA ILYLQTKLYD
     IVDHSDPVQL KEFHKLPSLL FKSDAVDGET EPTSLLSCPV GAATCAAVGG SKHKQQRADD
     DANKEEENMA KVMRVESPKS VEEADTCSIS SMSSSDCSNS QTQPLHGGAA GTAIGGAKSN
     AAPSVAGIAN VATKPFGGKD STKDSSAMPS TSRSSSGGIA RNRVIDQQFE LKIRRCLLYN
     KLVDLMPEAL CQPKKNVCDF VLP
//