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Database: UniProt
Entry: A0A182Q3E6_9DIPT
LinkDB: A0A182Q3E6_9DIPT
Original site: A0A182Q3E6_9DIPT 
ID   A0A182Q3E6_9DIPT        Unreviewed;       110 AA.
AC   A0A182Q3E6;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   03-JUL-2019, entry version 14.
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 9 {ECO:0000256|RuleBase:RU364145};
DE   AltName: Full=Mediator complex subunit 9 {ECO:0000256|RuleBase:RU364145};
GN   Name=MED9 {ECO:0000256|RuleBase:RU364145};
OS   Anopheles farauti.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicoidea;
OC   Culicidae; Anophelinae; Anopheles.
OX   NCBI_TaxID=69004 {ECO:0000313|Proteomes:UP000075886, ECO:0000313|VectorBase:AFAF002298-PA};
RN   [1] {ECO:0000313|Proteomes:UP000075886, ECO:0000313|VectorBase:AFAF002298-PA}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FAR1 {ECO:0000313|Proteomes:UP000075886,
RC   ECO:0000313|VectorBase:AFAF002298-PA};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W.,
RA   Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B.,
RA   Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C.,
RA   Murphy C., Pearson M., Poon T.W., Priest M., Roberts A., Saif S.,
RA   Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Anopheles farauti FAR1 (V2).";
RL   Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|VectorBase:AFAF002298-PA}
RP   IDENTIFICATION.
RC   STRAIN=FAR1 {ECO:0000313|VectorBase:AFAF002298-PA};
RG   VectorBase;
RL   Submitted (JUN-2016) to UniProtKB.
CC   -!- FUNCTION: Component of the Mediator complex, a coactivator
CC       involved in the regulated transcription of nearly all RNA
CC       polymerase II-dependent genes. Mediator functions as a bridge to
CC       convey information from gene-specific regulatory proteins to the
CC       basal RNA polymerase II transcription machinery. Mediator is
CC       recruited to promoters by direct interactions with regulatory
CC       proteins and serves as a scaffold for the assembly of a functional
CC       preinitiation complex with RNA polymerase II and the general
CC       transcription factors. {ECO:0000256|RuleBase:RU364145}.
CC   -!- SUBUNIT: Component of the Mediator complex.
CC       {ECO:0000256|RuleBase:RU364145}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU364145}.
CC   -!- SIMILARITY: Belongs to the Mediator complex subunit 9 family.
CC       {ECO:0000256|RuleBase:RU364145}.
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DR   EMBL; AXCN02001019; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   VectorBase; AFAF002298-RA; AFAF002298-PA; AFAF002298.
DR   Proteomes; UP000075886; Unassembled WGS sequence.
DR   GO; GO:0016592; C:mediator complex; IEA:InterPro.
DR   GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   InterPro; IPR011425; Med9.
DR   InterPro; IPR039242; MED9_metazoa.
DR   PANTHER; PTHR20844; PTHR20844; 1.
DR   Pfam; PF07544; Med9; 1.
PE   3: Inferred from homology;
KW   Activator {ECO:0000256|RuleBase:RU364145};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000075886};
KW   Nucleus {ECO:0000256|RuleBase:RU364145};
KW   Reference proteome {ECO:0000313|Proteomes:UP000075886};
KW   Transcription {ECO:0000256|RuleBase:RU364145};
KW   Transcription regulation {ECO:0000256|RuleBase:RU364145}.
FT   COILED       74    108       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   110 AA;  12880 MW;  453AF78B877141AB CRC64;
     MEVVETKPQI TNIPETKIQP VEIEILPVVY DIIRSVEKDP IDNTAKQKES AECSQKVLEL
     QRTLEASRNT IRKLQGIEHS KEEQLRRLES LRKQLALKQQ LIKKYKNVQF
//
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