ID A0A182QE14_9DIPT Unreviewed; 797 AA.
AC A0A182QE14;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 22-FEB-2023, entry version 26.
DE RecName: Full=FYVE-type domain-containing protein {ECO:0000259|PROSITE:PS50178};
OS Anopheles farauti.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=69004 {ECO:0000313|EnsemblMetazoa:AFAF008260-PA, ECO:0000313|Proteomes:UP000075886};
RN [1] {ECO:0000313|Proteomes:UP000075886}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FAR1 {ECO:0000313|Proteomes:UP000075886};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles farauti FAR1 (V2).";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AFAF008260-PA}
RP IDENTIFICATION.
RC STRAIN=FAR1 {ECO:0000313|EnsemblMetazoa:AFAF008260-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; AXCN02000028; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A182QE14; -.
DR STRING; 69004.A0A182QE14; -.
DR EnsemblMetazoa; AFAF008260-RA; AFAF008260-PA; AFAF008260.
DR VEuPathDB; VectorBase:AFAF008260; -.
DR OrthoDB; 277036at2759; -.
DR Proteomes; UP000075886; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15734; FYVE_ZFYV1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR042427; ZFYV1.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46624; AGAP002036-PA; 1.
DR PANTHER; PTHR46624:SF4; ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 1-LIKE PROTEIN; 1.
DR Pfam; PF01363; FYVE; 2.
DR SMART; SM00064; FYVE; 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50178; ZF_FYVE; 2.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 514..575
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT DOMAIN 755..797
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REGION 1..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 578..613
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 696..751
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 588..613
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 696..715
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 722..747
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 797 AA; 87958 MW; 168496BF9DACE1ED CRC64;
MMQAEDTESL SWISDKPPIT ADGTLAPSAQ PPDVVAGPFT SLPLDMTDTD DIDDRRSPAM
NGPTDTGSKK ERSFLLMDEQ ERICVRSAEQ FCKRLSVSPD TKLKVVSIFG NTGDGKSHTM
NHALFGGRDV FKTSSEQASC TMGIWAAFQR QKNVLALDTE GLLGETVNEN RQMRMLLKVL
AISDIIIYRT RAERLRTDMY KFLGTASKAF TKYFSGALQA LDLPGPPQAL GPAVIIFHET
HNTEVLKEDD DGKKEEDILR ERFAKLRLEL SAFSSLRYVG VRTAKPPTNY EPLRMVWEKE
IRNTAVRSPR LPRVVFEALL ALNNKFNGDL SPLPFNAFPE QYFTCTTYCK SCDARCQLSM
GHLELKEDHR CGSSCKYQHQ HENKVYLCNR CYVNGRQVVV SIKTQKSTDS SWMGLALYAW
SGSVIECPHC GEIYRSRQHW YGNKSPEQNA VRTEIVHVWN DGGLQLHGPT HSAQLVLDGV
AYITDAMASV GSQPTKLVKS WVTDKIRPAY WRPDSEIIHC KGCISNFDRL GLKKHHCRSC
GEGFCNHCSK HEMPVPSRGW NYPVRVCNSC WNDGRNGGTV GDAPMPGGQN GVTSNGNHQS
DQSHRMSGTA GNGIDEANNI LVRRYGEAVI NTITNIGAVL EYPKDFIKES ARPSYWVPDA
EAPNCYICEL EFGSPEELNT VNGPQAKATK ATAKLTNATL SPESSTPSAS PAKGTENGGV
ANGAVGSATT RTSSSSVQAA TKSRSSASYR SIDRRRHHCR ACGNAVCAGC SQHRRPVPKR
GWLSDVRVCN GCYTAED
//
