ID A0A182QGQ9_9DIPT Unreviewed; 1373 AA.
AC A0A182QGQ9;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};
OS Anopheles farauti.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=69004 {ECO:0000313|EnsemblMetazoa:AFAF009832-PA, ECO:0000313|Proteomes:UP000075886};
RN [1] {ECO:0000313|Proteomes:UP000075886}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FAR1 {ECO:0000313|Proteomes:UP000075886};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles farauti FAR1 (V2).";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AFAF009832-PA}
RP IDENTIFICATION.
RC STRAIN=FAR1 {ECO:0000313|EnsemblMetazoa:AFAF009832-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR005719}.
CC -!- SIMILARITY: Belongs to the SMC family. SMC4 subfamily.
CC {ECO:0000256|ARBA:ARBA00006005}.
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DR EMBL; AXCN02000606; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 69004.A0A182QGQ9; -.
DR EnsemblMetazoa; AFAF009832-RA; AFAF009832-PA; AFAF009832.
DR VEuPathDB; VectorBase:AFAF009832; -.
DR OrthoDB; 231904at2759; -.
DR Proteomes; UP000075886; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0051276; P:chromosome organization; IEA:InterPro.
DR Gene3D; 1.10.287.1490; -; 1.
DR Gene3D; 1.20.1060.20; -; 1.
DR Gene3D; 3.30.70.1620; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR024704; SMC.
DR InterPro; IPR010935; SMC_hinge.
DR InterPro; IPR036277; SMC_hinge_sf.
DR PANTHER; PTHR18937:SF172; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN; 1.
DR PANTHER; PTHR18937; STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; 1.
DR Pfam; PF06470; SMC_hinge; 1.
DR Pfam; PF02463; SMC_N; 1.
DR PIRSF; PIRSF005719; SMC; 1.
DR SMART; SM00968; SMC_hinge; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF75553; Smc hinge domain; 1.
DR SUPFAM; SSF57997; Tropomyosin; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|PIRNR:PIRNR005719}.
FT DOMAIN 607..723
FT /note="SMC hinge"
FT /evidence="ECO:0000259|SMART:SM00968"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 742..776
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1279..1373
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 261..288
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 342..369
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 433..573
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 778..847
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 872..1033
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 745..776
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1288..1327
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1335..1352
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1373 AA; 155598 MW; 13F44F433A04F66E CRC64;
MSAVKKRRTV GEGANKNAAA AAAAAQQQAQ QEPMDADVDD DALLSEDEEG GTRIGGIYIP
PPVPPYCSTE CKGPRLIIEC ITNYNFKSYA GHVTLGPFHQ RFSAIIGPNG SGKSNVIDSM
LFVFGYRAQK IRSKKLSVLL HNSSRHPNTN SCTVGVHFKQ IIDREDGSFD EVPNSAFVVA
RTAFRDNSSY YTIDNKRVHF KEVSKLLKQH GIDLDHNRFL ILQGEVESIA MMKSKAQTEN
ECGLLEYLED IVGTTRYKEP LLKINERVDA LNEERTEKHN RCKLAEREMK DLEKPMAEAV
EFLKQENTLT RTRNQQIQKY LSEQKRKIGE FEVEREQAAG ILAKHDETYE ALRAERVEKE
KLVKEEIKQY DALVASKEAK ETSLKNSLDK FAKVQANMRA TNERRKKTIE QIGVETKRLQ
ELQAVPAKNQ KEIEESEAKI ESLTKQKAET EAKLTENLAS LKDETKVLLE AKEKLQTELI
ELKRAVDESK SALSIAESEL KICKHDEVTE RRKLESLRYS YEETEKDLEE KRTRLQTLEQ
ALPATRTELE EAKQKLQTTA AEEREKRQEL RTVQGKLQEA MASVQSTRSQ GKVLDALMRQ
KNQGNIPGIL GRLGNLGGID ARYDVAISTC CGTLDHIVVE TADSATACIA FLKQNDIGRA
SFIALEKIQH LERNCHSKIQ TPENVPRLFD LVRVEDERVL PAFYFALRDT LVAENLDQGQ
RIAYGRQRFR VVTLGGDVIE TSGTMAGGGR SQQRGRMGTS VQTKTSASEP AGASRQEIEQ
LQVQQEDVNL QINQLQAQQR ELETLIQRLT GKLKNQEQEL TRMRLDVASL SQQMPRLKEQ
LDSQAERVAS THSDPEKVRA LEEKVAECKV VHEQSTGKAN KLQAEVDRYT TQINEITNSK
VKVLQTKITT LGKQIDKLSA NISKLTVEIK TSERNVKKSE DKIKSMEEEV AAAQASIRQG
NDERTQLEEE ADQLRTELEE MKQAIEKAHE GSSGIKKEIV ALQKREAEGK MKRLEFEQIL
QTIEAKLQET KDTLPHWRDK LKPLKLHEIP DTPPQEPLKE YTEEELSSYK LPDLQYQISI
LEEKLNANKP NLSVIEEFLR KREAFTQRVT VLEEITAKRN EMRQLYDDVR KKRFTEFMRG
FHIITKKLKE MYQMITLGGD AELELVDSMD PFNEGIVFSV RPPKKSWKMI SNLSGGEKTL
SSLALVFALH YYKPSPLYVM DEIDAALDFK NVSIVAHYIK ERTKNAQFII ISLRSNMFEL
SDYLVGIYKV SDCTNSVTIE NDPPKHESHL GATQQQTQQF SFPDQQNDNP APTEQGGTQN
GLEMVEMSEK TTENAPLEAV EKAVEKEPTG TEELAVESST AEPTGIRPMD VDE
//
