ID   A0A182QKZ0_9DIPT        Unreviewed;       873 AA.
AC   A0A182QKZ0;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   RecName: Full=Septin-type G domain-containing protein {ECO:0000259|PROSITE:PS51719};
OS   Anopheles farauti.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=69004 {ECO:0000313|EnsemblMetazoa:AFAF012314-PA, ECO:0000313|Proteomes:UP000075886};
RN   [1] {ECO:0000313|Proteomes:UP000075886}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FAR1 {ECO:0000313|Proteomes:UP000075886};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles farauti FAR1 (V2).";
RL   Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AFAF012314-PA}
RP   IDENTIFICATION.
RC   STRAIN=FAR1 {ECO:0000313|EnsemblMetazoa:AFAF012314-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC       GTPase superfamily. Septin GTPase family.
CC       {ECO:0000256|RuleBase:RU004560}.
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DR   EMBL; AXCN02002036; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A182QKZ0; -.
DR   STRING; 69004.A0A182QKZ0; -.
DR   EnsemblMetazoa; AFAF012314-RA; AFAF012314-PA; AFAF012314.
DR   VEuPathDB; VectorBase:AFAF012314; -.
DR   OrthoDB; 450367at2759; -.
DR   Proteomes; UP000075886; Unassembled WGS sequence.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   CDD; cd01850; CDC_Septin; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   InterPro; IPR030379; G_SEPTIN_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR016491; Septin.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR18884; SEPTIN; 1.
DR   PANTHER; PTHR18884:SF69; SEPTIN-RELATED; 1.
DR   Pfam; PF00735; Septin; 1.
DR   SMART; SM00028; TPR; 2.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS51719; G_SEPTIN; 1.
DR   PROSITE; PS50005; TPR; 2.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU004560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU004560};
KW   TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT   REPEAT          355..388
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          389..422
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   DOMAIN          495..761
FT                   /note="Septin-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51719"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          803..855
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   873 AA;  98349 MW;  D85C00BA4D658C7A CRC64;
     MANSSSGTEP SISKYFTNDP PSCFDSISAG EDGQTQDAIA EAYLSYDYLA ASSTDQQPNI
     PDSVRDLWEP PRVTPGVPPT SLTMPGVSVA TDLTDPVQDA VGLLVDANEA QQRKLLLPDN
     VTQDERGLRE LIEHGCFRSA VNLTARLLTI KQQGFGHAGH PVKHSPNSLQ LWFTRLALLV
     KLGQYEIARV EAEPFGALSN ADVFYEFYHP DMHADRKGSM APFSFRLLLA ELPVYLGAPR
     VALDRLTALL AIVNQIKVYF ERGTGTIPHA TDAHAFWTVR ETRILHSIVN CALAVKDFGL
     VEQLLERLVA AAATPQKRIL LSAWGRIRLQ CGDMVGAEKK FSEARRLKEE KSSEVPDLID
     RGLLAVAQND FQSAFDLFQK ASTAAPSNTM LYNNMGVCLL YSGKLKEAIK LYEGAIQRNT
     KSCLNESLLV NLSTLYELES NHAKEKKINL LKLVNRHRAD LTVGLDNDLT RSLKQSGHVG
     FDSLPDQLVS KSIQNGFVFN IMCIGETGLG KSTLMDSLFN TNFESQPSPH TMPSVKLKAH
     TYELQESTVR LKLTICDTVG YGDQINKDDS FKAVVDYIDL QFEAYLQEEL KIKRSLSTYH
     DSRTHICLYF ICPTGHGLKS LDLVCMKMLD SKVNIIPIIA KADTISKTEL TKFKSKINEE
     LAANGVQIYS FPTDDESVTE VNTTMNAHIP FAVVGSTDFV RIGNKTVRAR QYPWGTVQVE
     NEGHCDFVKL REMLIRTNME DMREKTHTRH YELYRQKRLE EMGFTDVDSE NKPVSFQQTF
     EAKRSNHLAE LQAKEDDVRQ MFVVRVKEKE AELKENEKEL HAKFDKLKKD HAEDKRKLEE
     SRKKLEEEFV EFNRRKSQMA THHTLTLGKS KKK
//