ID A0A182QLB7_9DIPT Unreviewed; 852 AA.
AC A0A182QLB7;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 03-MAY-2023, entry version 26.
DE RecName: Full=Armadillo segment polarity protein {ECO:0000256|ARBA:ARBA00022289};
OS Anopheles farauti.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=69004 {ECO:0000313|EnsemblMetazoa:AFAF012508-PA, ECO:0000313|Proteomes:UP000075886};
RN [1] {ECO:0000313|Proteomes:UP000075886}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FAR1 {ECO:0000313|Proteomes:UP000075886};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles farauti FAR1 (V2).";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AFAF012508-PA}
RP IDENTIFICATION.
RC STRAIN=FAR1 {ECO:0000313|EnsemblMetazoa:AFAF012508-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004413};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004413};
CC Cytoplasmic side {ECO:0000256|ARBA:ARBA00004413}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
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DR EMBL; AXCN02002161; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A182QLB7; -.
DR STRING; 69004.A0A182QLB7; -.
DR EnsemblMetazoa; AFAF012508-RA; AFAF012508-PA; AFAF012508.
DR VEuPathDB; VectorBase:AFAF012508; -.
DR OrthoDB; 50711at2759; -.
DR Proteomes; UP000075886; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0045296; F:cadherin binding; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd21726; CTNNAbd_dArm; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR013284; Beta-catenin.
DR PANTHER; PTHR45976; ARMADILLO SEGMENT POLARITY PROTEIN; 1.
DR PANTHER; PTHR45976:SF1; ARMADILLO SEGMENT POLARITY PROTEIN; 1.
DR Pfam; PF00514; Arm; 4.
DR PRINTS; PR01869; BCATNINFAMLY.
DR SMART; SM00185; ARM; 11.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 9.
PE 4: Predicted;
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687}.
FT REPEAT 156..196
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 198..241
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 240..282
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 282..324
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 324..367
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 405..447
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 447..484
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 494..537
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 604..647
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REGION 748..817
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 763..790
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 852 AA; 91963 MW; FF94B93D732E3E50 CRC64;
MMEYLQFLGE LSHNPYNPSD MPMPSAKEQT LMWQQNSYLG DSGIHSGAVT QVPSLSGKDD
DMEDDPLMFD MDQGFSQNFT QDQVDDMNQQ LSQTRSQRVR AAMFPETLEE GIEIPSTQFD
PQQPTAVQRL AEPSQMLKHA VVNLINYQDD ADLATRAIPE LIKLLNDEDQ VVVSQAAMMV
HQLSKKEASR HAIMNSPQMV AALVRALSNS NDLETTKGAV GTLHNLSHHR QGLLAIFKSG
GIPALVKLLS SPVESVLFYA ITTLHNLLLH QDGSKMAVRL AGGLQKMVAL LQRNNVKFLA
IVTDCLQILA YGNQESKLII LASTGPSELV RIMRSYDYEK LLWTTSRVLK VLSVCSSNKP
AIVEAGGMQA LAMHLGNPSQ RLVQNCLWTL RNLSDAATKV DGLETLLSGL VTVLGSSDVN
VVTCAAGILS NLTCNNQRNK VTVCQVGGVE ALVGTIINAG DREEITEPAV CALRHLTSRH
PESESAQNVV RNGYGLPVIV KLLNPPSRWP LIKAVIGLIR NLALCPANAA PLREHGAIHL
LVRLLFKAFQ DTQRQRSSVA TNGSQPPGAY ADGVRMEEIV EGTVGALHIL AKEEYNRQVI
RSQNVIPIFV QLLFYNDIEN IQRVAAGVLC ELAVDKEVAE MIEAEGATAP LTELLNSANE
GVATYAAAVL FKMSEDKSMD YKKRFSSELT TLPVFRDDSM WNNGELGIGP DLQAYEGLYG
QGPASVHSSH GGRAFQQGYD TLPIDSPMQG LEIGGGGGGS SVSNGGPAGN GMVGGPQQQQ
QQQQSAGGPG SSVVMGGGPV GMSSSGQPTS PYGMDMDVGE MDASELTFDH LDVMPSPPQD
NNQVAAWYDT DL
//
