ID A0A182QVK2_9DIPT Unreviewed; 1574 AA.
AC A0A182QVK2;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=KAP NTPase domain-containing protein {ECO:0000259|Pfam:PF07693};
OS Anopheles farauti.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=69004 {ECO:0000313|EnsemblMetazoa:AFAF017748-PA, ECO:0000313|Proteomes:UP000075886};
RN [1] {ECO:0000313|Proteomes:UP000075886}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FAR1 {ECO:0000313|Proteomes:UP000075886};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles farauti FAR1 (V2).";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AFAF017748-PA}
RP IDENTIFICATION.
RC STRAIN=FAR1 {ECO:0000313|EnsemblMetazoa:AFAF017748-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; AXCN02001696; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 69004.A0A182QVK2; -.
DR EnsemblMetazoa; AFAF017748-RA; AFAF017748-PA; AFAF017748.
DR VEuPathDB; VectorBase:AFAF017748; -.
DR OrthoDB; 5474354at2759; -.
DR Proteomes; UP000075886; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR011646; KAP_P-loop.
DR InterPro; IPR013761; SAM/pointed_sf.
DR PANTHER; PTHR24116; KINASE D-INTERACTING SUBSTRATE OF 220 KDA; 1.
DR PANTHER; PTHR24116:SF0; KINASE D-INTERACTING SUBSTRATE OF 220 KDA; 1.
DR Pfam; PF12796; Ank_2; 4.
DR Pfam; PF07693; KAP_NTPase; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 11.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 8.
DR PROSITE; PS50088; ANK_REPEAT; 9.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Membrane {ECO:0000256|SAM:Phobius}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 566..586
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 592..611
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 725..745
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 757..779
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 103..135
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 136..168
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 169..201
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 236..268
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 269..301
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 302..334
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 335..367
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 368..400
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 401..433
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 508..1037
FT /note="KAP NTPase"
FT /evidence="ECO:0000259|Pfam:PF07693"
FT REGION 934..953
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1258..1287
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1497..1542
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1574 AA; 171301 MW; 6B0A856CB51405FB CRC64;
LPICLADTSG PPNRASVLSL RFAIGGHEMK VIGYDELILN VQRLKAYGRR IARSSKVHAL
NRCDSMGSLG HRSLVQYLET DDLAGLKTFL GTRHLQVDDR DENNTTLLMS ASGRGASHFV
KELLARGADV QAQDLDNWTA LHFAAKAGHV GIVELLLDNG ADLEHRDMGG WTALMWGSYK
GHTGVVALLL QRGADVQAHG NYHLNPLLWA SGRGHTEIVR LLVNTGGAKV NVGDKYGTTP
LVWACRKGSA EIVDILLKAG ANVDTAGMYS WTPLLVAVSG GFQECVTLLL ERKPNVNALD
KDGMTALSIA CREGLTEIAS GLIAVGAYLN VQDRAGDTPL INAVKGGHRS VVEILMKRHV
DVDIQGKDKK TALYTAVEKG HTAIVKLILQ SNPDLELSTK DGDTALLRAV RNRNLEIVQM
LLERKAKVGA TDKRGDTCLH VAMRARSKAI VEALLSNPKY GQLLYRSNKE GETPYAIDAA
HQKTILGQVF GNRRLNANED SEGMLGYGLY SSALADVLSE PTLTTPITVG LYAKWGSGKS
FLLTELRDEM KNFAHSWTEP PIDASVLFFL ISLHLALVLG TVVGLATWSY VWGLATGAVL
LVLIYFTDIL FKFLDRRYDL EWLYTLNYGL SRKLGRLRLI LQVAFCHPPG PQSDQQPMPV
RFHFAEASGA APNGDAAVAL MLASLFDAIE THYGSLATGL YRAFRPKPLK ATGGWKWRKM
CCMPVVLMFE LGMLGILATA SLSIIYSEYG LEARDEIAVA IYVLLGILLA GAIANLHAWS
KLIGALFMSQ GKHLKRAFNS NEAAPLTALG AEVSLMTDMV RCLDAFTGQQ SRLVGVVDAL
DSCDTERTLT ILNAVQTLLS GPQRPFVLLL AVDPHVIAKA AEANSRRLFT EGGIGGHDFL
RNLVHLPVYL QNSGLRKVQR AQNTALSAYR RAMPDLSRDD DQPHLGHSAS ARRLSNASEI
MSSQEKLRAM PSSSRGGSKK LRVSDSIASS IGSNLHKLGQ NPPVDLSKII LTDDYFSDVN
PRSMRRLMNV IYITVRLLKA FQIDFSWYRL SSWINLTEQW PLRASMIVLE HDQAGDSIDD
SVSLQAVYDK VRPKLTCLRE AAALLDLDRD ERKLDAFLQL HKSDLMVSDL RIFLPFTINL
DPYLRKVLKE DQQALEDEGI IIPMKTVLPP SKPAGFMSTS HHHRAHGANV LQPTPHHPNS
LTNWPNFYNP QQAPAMALMN FYNPNWTNLM NSGGPMAEAI NKPGPVGGGA IIMEHEQHST
GAGSSGGRGK GTSTNHKTTN GLPTTPPIDI DLSNVQLSNL TVDQLVDLLG QVNDLKPAME
RMAPILRENA ISGRVLMYCN LDELKSVLRL SFGHWEMFKL LVTALREATV TQPPSRKLPK
TTTFAKGAND TVELQEPIAQ STPPFGSSSS SFQPIRQKSQ NLLEKQVTLE EQMICGALQT
LNEDAFEDVV SSSERPSPTG EMFSQFLAPI RESSEIGSPP RLTYNLTNPN LTDLATSNGT
LNGDDGGGGG GVVGGVAGGG GGSSVHLGPR TGSGRHSRSH SLHDDASLTS ILVIPPFLTA
SANTTTSNIN DTKL
//
