ID   A0A182QX33_9DIPT        Unreviewed;       578 AA.
AC   A0A182QX33;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:AFAF018603-PA};
OS   Anopheles farauti.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=69004 {ECO:0000313|EnsemblMetazoa:AFAF018603-PA, ECO:0000313|Proteomes:UP000075886};
RN   [1] {ECO:0000313|Proteomes:UP000075886}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FAR1 {ECO:0000313|Proteomes:UP000075886};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles farauti FAR1 (V2).";
RL   Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AFAF018603-PA}
RP   IDENTIFICATION.
RC   STRAIN=FAR1 {ECO:0000313|EnsemblMetazoa:AFAF018603-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
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DR   EMBL; AXCN02001449; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A182QX33; -.
DR   STRING; 69004.A0A182QX33; -.
DR   EnsemblMetazoa; AFAF018603-RA; AFAF018603-PA; AFAF018603.
DR   VEuPathDB; VectorBase:AFAF018603; -.
DR   OrthoDB; 2996885at2759; -.
DR   Proteomes; UP000075886; Unassembled WGS sequence.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR   InterPro; IPR002404; IRS_PTB.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   PANTHER; PTHR21258; DOCKING PROTEIN RELATED; 1.
DR   PANTHER; PTHR21258:SF56; INSULIN RECEPTOR SUBSTRATE 1; 1.
DR   Pfam; PF02174; IRS; 1.
DR   SMART; SM01244; IRS; 1.
DR   SMART; SM00233; PH; 1.
DR   SMART; SM00310; PTBI; 1.
DR   SUPFAM; SSF50729; PH domain-like; 2.
DR   PROSITE; PS51064; IRS_PTB; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   4: Predicted;
FT   DOMAIN          22..124
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   DOMAIN          152..258
FT                   /note="IRS-type PTB"
FT                   /evidence="ECO:0000259|PROSITE:PS51064"
FT   REGION          318..344
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          372..391
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          466..511
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          536..561
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        476..492
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        497..511
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        543..561
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   578 AA;  64422 MW;  18EE194E6774A7BB CRC64;
     LSPSCPSHGL SNSIVKMDEE ENPFLVGYLT VKSQSGFSWR VTKKLKYCQL YKASRHGIER
     LEISDAETDK NTRIVTLENC VKIVLDQPPQ NTINIVSKTG QIQLYAPDEA LVRQWTNALQ
     IVAFKDKSNQ PPPPPRLNTI EEDNDLYCSS YSEGIYTVTL IPTDASIKNG LEPKMYTLEL
     GQMDMRLKCY EDESVTVAMW PYRYIRKYGY REGKFTFEAG RKCNTGEGTF KLDNASPQDI
     FRCMLTKMKS MKKIISHTSE HESHALSSQL CAALAMEPGS RSPLPGVHCE ENITSHLSSF
     ELLHDIVPVM ATITQLKSIP TKPPRKQSTS PGLAVPPDTD PKQSNVSTVF IKQCTSQQQQ
     PAASPASTIL IRNLTGDDGP PVGAGPPPAG KELDYECVKD ITDAWKRYGL NDVKHTEAVA
     DGAFPPVPLP PPDHVRPIEY DRLDFFRTTT RHPSADYKTI VPVRLAGERG TTPPPHQRLP
     TATATSSSDD YEIIGEPSPP PLGPPPPPPL GYNVSGVRRV LDDGFDFSVF NTSNEHHLDH
     QEQQQQQQQQ HQQLQQQQQQ RNIAATINYA TISKPKRV
//