ID A0A182QX52_9DIPT Unreviewed; 698 AA.
AC A0A182QX52;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 22-FEB-2023, entry version 26.
DE RecName: Full=U3 small nucleolar ribonucleoprotein protein MPP10 {ECO:0000256|PIRNR:PIRNR017300};
OS Anopheles farauti.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=69004 {ECO:0000313|EnsemblMetazoa:AFAF018634-PA, ECO:0000313|Proteomes:UP000075886};
RN [1] {ECO:0000313|Proteomes:UP000075886}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FAR1 {ECO:0000313|Proteomes:UP000075886};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles farauti FAR1 (V2).";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AFAF018634-PA}
RP IDENTIFICATION.
RC STRAIN=FAR1 {ECO:0000313|EnsemblMetazoa:AFAF018634-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- FUNCTION: Involved in nucleolar processing of pre-18S ribosomal RNA.
CC {ECO:0000256|PIRNR:PIRNR017300}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604, ECO:0000256|PIRNR:PIRNR017300}.
CC -!- SIMILARITY: Belongs to the MPP10 family.
CC {ECO:0000256|ARBA:ARBA00029455, ECO:0000256|PIRNR:PIRNR017300}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AXCN02002086; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A182QX52; -.
DR STRING; 69004.A0A182QX52; -.
DR EnsemblMetazoa; AFAF018634-RA; AFAF018634-PA; AFAF018634.
DR VEuPathDB; VectorBase:AFAF018634; -.
DR OrthoDB; 181024at2759; -.
DR Proteomes; UP000075886; Unassembled WGS sequence.
DR GO; GO:0034457; C:Mpp10 complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005732; C:sno(s)RNA-containing ribonucleoprotein complex; IEA:UniProtKB-UniRule.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR InterPro; IPR012173; Mpp10.
DR PANTHER; PTHR17039; U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10; 1.
DR PANTHER; PTHR17039:SF0; U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10; 1.
DR Pfam; PF04006; Mpp10; 1.
DR PIRSF; PIRSF017300; snoRNP_Mpp10; 2.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR017300};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW ECO:0000256|PIRNR:PIRNR017300};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517,
KW ECO:0000256|PIRNR:PIRNR017300};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552,
KW ECO:0000256|PIRNR:PIRNR017300}.
FT REGION 121..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 206..311
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 327..370
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 569..624
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 639..698
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 149..164
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 206..221
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 232..306
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 352..370
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 569..593
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 600..617
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 639..669
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 670..690
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 698 AA; 80443 MW; 60CA59744E38AC27 CRC64;
MVKAHIVSPL LMKPEKEGLK SHVKLFRKYT KQPANYLKIQ KPVAKKLKLL VKNIYDHATK
NPIVANDEPV PYLDELVTEE MDDEQIWQQL ELKNDHFIDQ DLKNFLDVVS KNEKRLQLEF
SRQALTEDGS DEDEGSDNGD MQESGDENDH NGEEMESGEE NGVDDSDEER PKKAKKQKKN
VKSKSKEKKS IVDDRFFKLD DMARFLDEED ERERRKQNGL GEKNPLIDID YFDENLGDDD
DDAAEMKYSD FFDDEDDVED DEDDSAEEEA DEEEETEKDV DEREDDVDEN EEDEEEPPVE
DAELSDEAEV ERNRKLRYEI YKGYGALEDL GTARDLPAKN TVIDQPDSSD SEEDVEVKSN
GPKSSYEQRQ EKLKEKISNM EARLLKDKPW QLKGEITGET RPMNSLLEEV LEYEHTTRPA
PVVSEETTMR LEDIIKQRIR NKAYDDVERK VRPPDNPREY RKQLVLDGEK SKQSLAQVYE
QDYLKQLEKA NPDADVQAGE EEEPKEHKEI RLMMKTVLAQ LDALSNFHYT PRPAAPEVKI
LTNTPAISME EVAPVATSDA TLLAPEEVHR RPKGDVMSKE ERTKTDQNRE RRLKKRFQQN
KFKREAEREK KQMEKAAAGD NKSIQNRALQ ASLLKKVTKA KNVQQMVETS AGPAKSSSAF
FSQLQDEVRA QTKSKADGTS NKKKKKNTEN LNASSFKL
//
