ID A0A182R2R0_ANOFN Unreviewed; 730 AA.
AC A0A182R2R0;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 13-SEP-2023, entry version 27.
DE SubName: Full=THO complex subunit 5 {ECO:0000313|EnsemblMetazoa:AFUN000451-PA};
OS Anopheles funestus (African malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=62324 {ECO:0000313|EnsemblMetazoa:AFUN000451-PA, ECO:0000313|Proteomes:UP000075900};
RN [1] {ECO:0000313|Proteomes:UP000075900}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FUMOZ {ECO:0000313|Proteomes:UP000075900};
RX PubMed=21129198; DOI=10.1186/1756-3305-3-117;
RA Sinka M.E., Bangs M.J., Manguin S., Coetzee M., Mbogo C.M., Hemingway J.,
RA Patil A.P., Temperley W.H., Gething P.W., Kabaria C.W., Okara R.M.,
RA Van Boeckel T., Godfray H.C., Harbach R.E., Hay S.I.;
RT "The dominant Anopheles vectors of human malaria in Africa, Europe and the
RT Middle East: occurrence data, distribution maps and bionomic precis.";
RL Parasit. Vectors 3:117-117(2010).
RN [2] {ECO:0000313|Proteomes:UP000075900}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FUMOZ {ECO:0000313|Proteomes:UP000075900};
RX PubMed=31157884; DOI=10.1093/gigascience/giz063;
RA Ghurye J., Koren S., Small S.T., Redmond S., Howell P., Phillippy A.M.,
RA Besansky N.J.;
RT "A chromosome-scale assembly of the major African malaria vector Anopheles
RT funestus.";
RL Gigascience 8:0-0(2019).
RN [3] {ECO:0000313|EnsemblMetazoa:AFUN000451-PA}
RP IDENTIFICATION.
RC STRAIN=FUMOZ {ECO:0000313|EnsemblMetazoa:AFUN000451-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the THOC5 family.
CC {ECO:0000256|ARBA:ARBA00008044}.
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DR AlphaFoldDB; A0A182R2R0; -.
DR STRING; 62324.A0A182R2R0; -.
DR EnsemblMetazoa; AFUN000451-RA; AFUN000451-PA; AFUN000451.
DR VEuPathDB; VectorBase:AFUN000451; -.
DR VEuPathDB; VectorBase:AFUN2_012415; -.
DR OrthoDB; 52790at2759; -.
DR Proteomes; UP000075900; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR InterPro; IPR019163; THO_Thoc5.
DR PANTHER; PTHR13375; FMS INTERACTING PROTEIN; 1.
DR PANTHER; PTHR13375:SF3; THO COMPLEX SUBUNIT 5 HOMOLOG; 1.
DR Pfam; PF09766; FmiP_Thoc5; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 316..367
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 325..346
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 730 AA; 83027 MW; A57148FF40BB7754 CRC64;
MVSKPDNNET VTDKKRRKTS SSNATDNSAS SAKTSKEDVY MNTIAFEEQE ASKRSPVKDA
NLFHATCDEL RTIFGDIAKL KADNSEDTKM KIADKRIEGS LAFVLLKKLN RLDKVRIREG
RDALHKEKLR VDSNRLQLQN LLYEAEHLKR EVQRCYMFKS QDEEIELVPV EEFYQQAPES
VSRPETTKTD EHARRIARLE WELQQRKELD AHLKELLTLK QAVEKDIIAK TARLDSLGPR
LRDLLIATRP LQEALEMPVE KGWKIRKTVR LLPQPLYLLY ANVTAYGEAC DNFLVTSIQG
DEEEAKQMAA AINSYESETH CGSDSGNNSR DRADSDNDEN EHEVHRGMKK RHHRGHIKTN
LDEQRREKLL KPHPLSVTIT IRAKDCPTEL STDHLSGPGL SLTFTYLPNM QVVTVNIALV
DLHSSGVAAG DVLSTESVLN ELFRGDKGEE CPNPKIKYQL QDLSIEINQL ARILKEKELG
KPFLWAQKLC GLEHTSTVYT SVRIGPDALG NEPLEVTDKL HETIPSIVRS VRARWEARLK
LYKQIHDLET KMIDTSINDE RGHPIRISST VLQWSSISFE DYVSSGVAKL FLEDGMATAS
DLYFRAIVIR GSAKLECYIC VPCRFPDNSP LWSFSLNWNG KHTSSCNSSV REMEYWSNSL
AAAEHSFDIL PKQLKRAMSC LDIYLETEGP YYTPAEFTQD KSFLKPFRGR TRAQPFRIAP
NGSSSLFTQI
//
