ID A0A182R3Z4_ANOFN Unreviewed; 522 AA.
AC A0A182R3Z4;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 2.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=Ras-associating domain-containing protein {ECO:0000259|PROSITE:PS50200};
OS Anopheles funestus (African malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=62324 {ECO:0000313|EnsemblMetazoa:AFUN000885-PA, ECO:0000313|Proteomes:UP000075900};
RN [1] {ECO:0000313|Proteomes:UP000075900}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FUMOZ {ECO:0000313|Proteomes:UP000075900};
RX PubMed=21129198; DOI=10.1186/1756-3305-3-117;
RA Sinka M.E., Bangs M.J., Manguin S., Coetzee M., Mbogo C.M., Hemingway J.,
RA Patil A.P., Temperley W.H., Gething P.W., Kabaria C.W., Okara R.M.,
RA Van Boeckel T., Godfray H.C., Harbach R.E., Hay S.I.;
RT "The dominant Anopheles vectors of human malaria in Africa, Europe and the
RT Middle East: occurrence data, distribution maps and bionomic precis.";
RL Parasit. Vectors 3:117-117(2010).
RN [2] {ECO:0000313|Proteomes:UP000075900}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FUMOZ {ECO:0000313|Proteomes:UP000075900};
RX PubMed=31157884; DOI=10.1093/gigascience/giz063;
RA Ghurye J., Koren S., Small S.T., Redmond S., Howell P., Phillippy A.M.,
RA Besansky N.J.;
RT "A chromosome-scale assembly of the major African malaria vector Anopheles
RT funestus.";
RL Gigascience 8:0-0(2019).
RN [3] {ECO:0000313|EnsemblMetazoa:AFUN000885-PA}
RP IDENTIFICATION.
RC STRAIN=FUMOZ {ECO:0000313|EnsemblMetazoa:AFUN000885-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR AlphaFoldDB; A0A182R3Z4; -.
DR EnsemblMetazoa; AFUN000885-RA; AFUN000885-PA; AFUN000885.
DR VEuPathDB; VectorBase:AFUN000885; -.
DR VEuPathDB; VectorBase:AFUN2_005960; -.
DR OrthoDB; 2911765at2759; -.
DR Proteomes; UP000075900; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd17043; RA; 1.
DR InterPro; IPR000159; RA_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR21298:SF2; GH01721P; 1.
DR PANTHER; PTHR21298; UNCHARACTERIZED; 1.
DR Pfam; PF00788; RA; 2.
DR SMART; SM00314; RA; 2.
DR SUPFAM; SSF54236; Ubiquitin-like; 2.
DR PROSITE; PS50200; RA; 2.
PE 4: Predicted;
FT DOMAIN 57..150
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
FT DOMAIN 151..243
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
FT REGION 25..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 276..307
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 343..433
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 276..301
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 344..382
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 393..428
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 522 AA; 57618 MW; 948BE72BDD82B2B1 CRC64;
MLKHVQISPM RSRADSLSMR SSTSCASSLC GSPEPPGDQL RSHSRASSYS SLNETIPQTT
IKIYTACLRQ DIEYKTLGIS YDATSKSVVQ QVLRRCKMRH RDPRLFYLTM EVTVRRPGVK
SVLELDDEAR PALLQACHPK GDSRFCLQQK PGGLIRVHTS ALQPNSQYKS LLISEETTSD
ELLSLLLSCY NSIEPVEQFS LYEVCPGQEY QRKLHPDDLP LKTQLQRQQK GEIMHFLVRR
NPNYPRRRQL LATIAESKHF ILNSSLDSAN VQHPAAGIHH HHHHHHQQQQ NHHHHHHRLS
LHSGSFSLGP TGTPTNTFIS DIVDGLSSLN DLPAEAKSLR LKESSSFCPA SLDDSATSTD
STDSTESSSS SCSSFSSLSS DSSFEEPEKH TIDNTSNVTQ TSSCHQALPP EVKSKNSAQH
QQPPPRPAKS SSMLAALSRP ALLPVSTLAA PSYNPVYNIR EIRTVSQSFS ALGIDKKLAD
IRSSTGVKTN TTESGGTVRS SALLKEMVNT DPAKGVGNFV YI
//
