ID A0A182R7H0_ANOFN Unreviewed; 641 AA.
AC A0A182R7H0;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 2.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=ZZ-type domain-containing protein {ECO:0000313|EnsemblMetazoa:AFUN002119-PA};
OS Anopheles funestus (African malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=62324 {ECO:0000313|EnsemblMetazoa:AFUN002119-PA, ECO:0000313|Proteomes:UP000075900};
RN [1] {ECO:0000313|Proteomes:UP000075900}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FUMOZ {ECO:0000313|Proteomes:UP000075900};
RX PubMed=21129198; DOI=10.1186/1756-3305-3-117;
RA Sinka M.E., Bangs M.J., Manguin S., Coetzee M., Mbogo C.M., Hemingway J.,
RA Patil A.P., Temperley W.H., Gething P.W., Kabaria C.W., Okara R.M.,
RA Van Boeckel T., Godfray H.C., Harbach R.E., Hay S.I.;
RT "The dominant Anopheles vectors of human malaria in Africa, Europe and the
RT Middle East: occurrence data, distribution maps and bionomic precis.";
RL Parasit. Vectors 3:117-117(2010).
RN [2] {ECO:0000313|Proteomes:UP000075900}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FUMOZ {ECO:0000313|Proteomes:UP000075900};
RX PubMed=31157884; DOI=10.1093/gigascience/giz063;
RA Ghurye J., Koren S., Small S.T., Redmond S., Howell P., Phillippy A.M.,
RA Besansky N.J.;
RT "A chromosome-scale assembly of the major African malaria vector Anopheles
RT funestus.";
RL Gigascience 8:0-0(2019).
RN [3] {ECO:0000313|EnsemblMetazoa:AFUN002119-PA}
RP IDENTIFICATION.
RC STRAIN=FUMOZ {ECO:0000313|EnsemblMetazoa:AFUN002119-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR AlphaFoldDB; A0A182R7H0; -.
DR STRING; 62324.A0A182R7H0; -.
DR EnsemblMetazoa; AFUN002119-RA; AFUN002119-PA; AFUN002119.
DR VEuPathDB; VectorBase:AFUN002119; -.
DR VEuPathDB; VectorBase:AFUN2_006478; -.
DR OrthoDB; 4105031at2759; -.
DR Proteomes; UP000075900; Unassembled WGS sequence.
DR GO; GO:0016010; C:dystrophin-associated glycoprotein complex; IEA:UniProt.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0007154; P:cell communication; IEA:UniProt.
DR GO; GO:0050804; P:modulation of chemical synaptic transmission; IEA:UniProt.
DR GO; GO:0046716; P:muscle cell cellular homeostasis; IEA:UniProt.
DR GO; GO:0023052; P:signaling; IEA:UniProt.
DR CDD; cd02345; ZZ_dah; 1.
DR Gene3D; 3.30.60.90; -; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR015153; EF-hand_dom_typ1.
DR InterPro; IPR000433; Znf_ZZ.
DR InterPro; IPR043145; Znf_ZZ_sf.
DR PANTHER; PTHR12268:SF21; DISCONTINUOUS ACTIN HEXAGON; 1.
DR PANTHER; PTHR12268; E3 UBIQUITIN-PROTEIN LIGASE KCMF1; 1.
DR Pfam; PF09068; EF-hand_2; 1.
DR Pfam; PF00569; ZZ; 1.
DR SMART; SM00291; ZnF_ZZ; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50135; ZF_ZZ_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00228}.
FT DOMAIN 262..317
FT /note="ZZ-type"
FT /evidence="ECO:0000259|PROSITE:PS50135"
FT COILED 419..446
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 613..640
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 641 AA; 73402 MW; B7846A974169C0B7 CRC64;
MMYDQQIDER GYLLYRNRYN GKTEQDNPNL LFILLTINEK YAGSRYSTYR CAGKLHAFQK
ALYISYIPFE MVHSILNRHQ LNLIDSAPSI KPSQLISVVH DIYFAATRMG YFDELTAPPN
LDAVSAILAS FFWAVFDPKR SNLVSVLELR QTFLLLCDHT SHAQLVWEHF RLTSDHNLCV
SRHRFEAMLT VLSKVLTFLG EPDHLRPSMV QQITGECFAN YPGLVGLTEY QFSCLWKLSS
LFSYYANVVS LCKRLRDTEH TTHGMLCYGC RITIRGLRFK CQRCRQVSLC IECFTSGYSN
KRHNMAHKMY EISSSDTDDG SRCNAWAGKL WRWLKTTNNP TGGTGGGIPT SPSTYENLEA
KLLDTKAVDL MQGEEVCVVQ EHEGDGDRKN TQRRESMVNS TLKRNMSLFS SVEYGVFNNT
QQKNLLAKLA VLVETLEEQH EATRKRKVEC WQGLTDEQRQ MTDGMHTLFE NFVAQVAEGL
TQLKDIGTQL GQGLPQCSST PYRQAAITSD CTADATQEKS VGRSRIMEKT ELSVRDISTW
FHIELDRGQQ TGETEGKDST LPPVITEERT LKRDELSCRI DRLKMDTQMV NFRDLLLKVR
EIVDDSYSDN TELARSTQQI EKALDRIIAE EEQKRSQQQL L
//
