ID A0A182RHS7_ANOFN Unreviewed; 146 AA.
AC A0A182RHS7;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 2.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=tRNA-splicing endonuclease subunit Sen15 domain-containing protein {ECO:0000259|Pfam:PF09631};
OS Anopheles funestus (African malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=62324 {ECO:0000313|EnsemblMetazoa:AFUN005789-PA, ECO:0000313|Proteomes:UP000075900};
RN [1] {ECO:0000313|Proteomes:UP000075900}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FUMOZ {ECO:0000313|Proteomes:UP000075900};
RX PubMed=21129198; DOI=10.1186/1756-3305-3-117;
RA Sinka M.E., Bangs M.J., Manguin S., Coetzee M., Mbogo C.M., Hemingway J.,
RA Patil A.P., Temperley W.H., Gething P.W., Kabaria C.W., Okara R.M.,
RA Van Boeckel T., Godfray H.C., Harbach R.E., Hay S.I.;
RT "The dominant Anopheles vectors of human malaria in Africa, Europe and the
RT Middle East: occurrence data, distribution maps and bionomic precis.";
RL Parasit. Vectors 3:117-117(2010).
RN [2] {ECO:0000313|Proteomes:UP000075900}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FUMOZ {ECO:0000313|Proteomes:UP000075900};
RX PubMed=31157884; DOI=10.1093/gigascience/giz063;
RA Ghurye J., Koren S., Small S.T., Redmond S., Howell P., Phillippy A.M.,
RA Besansky N.J.;
RT "A chromosome-scale assembly of the major African malaria vector Anopheles
RT funestus.";
RL Gigascience 8:0-0(2019).
RN [3] {ECO:0000313|EnsemblMetazoa:AFUN005789-PA}
RP IDENTIFICATION.
RC STRAIN=FUMOZ {ECO:0000313|EnsemblMetazoa:AFUN005789-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SEN15 family.
CC {ECO:0000256|ARBA:ARBA00006091}.
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DR AlphaFoldDB; A0A182RHS7; -.
DR STRING; 62324.A0A182RHS7; -.
DR EnsemblMetazoa; AFUN005789-RA; AFUN005789-PA; AFUN005789.
DR VEuPathDB; VectorBase:AFUN005789; -.
DR OrthoDB; 3412082at2759; -.
DR Proteomes; UP000075900; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; IEA:InterPro.
DR Gene3D; 3.40.1350.10; -; 1.
DR InterPro; IPR018593; tRNA-endonuc_su_Sen15.
DR InterPro; IPR011856; tRNA_endonuc-like_dom_sf.
DR InterPro; IPR036167; tRNA_intron_Endo_cat-like_sf.
DR PANTHER; PTHR28582; TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN15; 1.
DR PANTHER; PTHR28582:SF1; TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN15; 1.
DR Pfam; PF09631; Sen15; 1.
DR SUPFAM; SSF53032; tRNA-intron endonuclease catalytic domain-like; 1.
PE 3: Inferred from homology;
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 28..124
FT /note="tRNA-splicing endonuclease subunit Sen15"
FT /evidence="ECO:0000259|Pfam:PF09631"
SQ SEQUENCE 146 AA; 17121 MW; E6532A9D519A732B CRC64;
MDNFHEILKT FYSFDCKDEA LCYAACRVYS FLREEKRMID VRYQFKNELQ LFYLIAKKEL
EAAFNLFIPS VTTGQLNLVQ LKYYRDTLKL PDGRKPEYII LAVCDPSSTV LLYRMTLGLK
EIRQKLPSKG KLLRLKAESG YDKGSH
//