ID A0A182S4R8_ANOFN Unreviewed; 616 AA.
AC A0A182S4R8;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=LIM zinc-binding domain-containing protein {ECO:0000259|PROSITE:PS50023};
OS Anopheles funestus (African malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=62324 {ECO:0000313|EnsemblMetazoa:AFUN015789-PA, ECO:0000313|Proteomes:UP000075900};
RN [1] {ECO:0000313|Proteomes:UP000075900}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FUMOZ {ECO:0000313|Proteomes:UP000075900};
RX PubMed=21129198; DOI=10.1186/1756-3305-3-117;
RA Sinka M.E., Bangs M.J., Manguin S., Coetzee M., Mbogo C.M., Hemingway J.,
RA Patil A.P., Temperley W.H., Gething P.W., Kabaria C.W., Okara R.M.,
RA Van Boeckel T., Godfray H.C., Harbach R.E., Hay S.I.;
RT "The dominant Anopheles vectors of human malaria in Africa, Europe and the
RT Middle East: occurrence data, distribution maps and bionomic precis.";
RL Parasit. Vectors 3:117-117(2010).
RN [2] {ECO:0000313|Proteomes:UP000075900}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FUMOZ {ECO:0000313|Proteomes:UP000075900};
RX PubMed=31157884; DOI=10.1093/gigascience/giz063;
RA Ghurye J., Koren S., Small S.T., Redmond S., Howell P., Phillippy A.M.,
RA Besansky N.J.;
RT "A chromosome-scale assembly of the major African malaria vector Anopheles
RT funestus.";
RL Gigascience 8:0-0(2019).
RN [3] {ECO:0000313|EnsemblMetazoa:AFUN015789-PA}
RP IDENTIFICATION.
RC STRAIN=FUMOZ {ECO:0000313|EnsemblMetazoa:AFUN015789-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR AlphaFoldDB; A0A182S4R8; -.
DR STRING; 62324.A0A182S4R8; -.
DR EnsemblMetazoa; AFUN015789-RA; AFUN015789-PA; AFUN015789.
DR VEuPathDB; VectorBase:AFUN015789; -.
DR VEuPathDB; VectorBase:AFUN2_005785; -.
DR OrthoDB; 370973at2759; -.
DR Proteomes; UP000075900; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd09351; LIM1_LPP; 1.
DR CDD; cd09354; LIM2_LPP; 1.
DR CDD; cd09437; LIM3_LPP; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 3.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR24207; ZYX102 PROTEIN; 1.
DR PANTHER; PTHR24207:SF2; ZYX102 PROTEIN; 1.
DR Pfam; PF00412; LIM; 3.
DR SMART; SM00132; LIM; 3.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 3.
DR PROSITE; PS00478; LIM_DOMAIN_1; 1.
DR PROSITE; PS50023; LIM_DOMAIN_2; 2.
PE 4: Predicted;
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00125};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 417..478
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 537..607
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT REGION 15..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 143..167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 209..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 248..268
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..167
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 616 AA; 67175 MW; 34F9CA249B58204C CRC64;
MEDLKEQFPA YNSVLRQSNG QQRPYHSTGL PDCPPNGAGI PGMVMIGRKN GPAVPPKPRK
NGQQQVPPQV PKSSNVKQYC EPSFSTLLEG QATNLDEHAY TNVTNATNGV TNTARGGKLG
ARKVTLDDAL ELQHVKEALE HHKRTLEANR SKSLQGQGPE HSNTVYENTQ PASYAGSYAS
DATYSNLPGA PHPGHQGGKN NEGLIYSNIM HNTNPSKPFP QRQISEELPP PPPQDMSLQL
TLNALNLEDN DDEFPPPPSP VSSSYSELRR ATDLPHMGRQ SQPTYTLVGP GAGGVGAPGG
QTYSNMAPGS QIYANNMHHQ SLYGTYGMSS QGSTTYESIY EPINPRPPSQ MSGRSNYSLY
APYVNSHGIN SPNDSIITSA SQQQHRGHGG NTMSKGAEVD TLTDLLVQSI QDQESFGTCV
KCGERVVGEK TGCTAMDKIY HIACFTCHQC QINLQGKPFY GLDGKPYCKE DYLNTLEKCS
VCLKPILERI LRATGKPYHP QCFTCIVCGK SLDGIPFTVD ATNQIHCIDD FHKKFAPRCC
VCKLPIMPGP GEDETVRVVA LDRSFHINCY KCEDCGLVLS SEAEGRGCYP LDDHILCKSC
NAKRVQTLTS HMTTEL
//
