ID   A0A182S8Q5_9DIPT        Unreviewed;       662 AA.
AC   A0A182S8Q5;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=Transcription initiation factor TFIID subunit 6 {ECO:0000256|ARBA:ARBA00040091};
OS   Anopheles maculatus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles; Anopheles maculatus group.
OX   NCBI_TaxID=74869 {ECO:0000313|EnsemblMetazoa:AMAM001923-PA, ECO:0000313|Proteomes:UP000075901};
RN   [1] {ECO:0000313|Proteomes:UP000075901}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=maculatus3 {ECO:0000313|Proteomes:UP000075901};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles maculatus species B.";
RL   Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AMAM001923-PA}
RP   IDENTIFICATION.
RC   STRAIN=maculatus3 {ECO:0000313|EnsemblMetazoa:AMAM001923-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the TAF6 family.
CC       {ECO:0000256|ARBA:ARBA00007688}.
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DR   AlphaFoldDB; A0A182S8Q5; -.
DR   EnsemblMetazoa; AMAM001923-RA; AMAM001923-PA; AMAM001923.
DR   VEuPathDB; VectorBase:AMAM001923; -.
DR   OrthoDB; 1529at2759; -.
DR   Proteomes; UP000075901; Unassembled WGS sequence.
DR   GO; GO:0000124; C:SAGA complex; IEA:InterPro.
DR   GO; GO:0046695; C:SLIK (SAGA-like) complex; IEA:InterPro.
DR   GO; GO:0005669; C:transcription factor TFIID complex; IEA:InterPro.
DR   GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR   GO; GO:0016251; F:RNA polymerase II general transcription initiation factor activity; IEA:InterPro.
DR   GO; GO:0006367; P:transcription initiation at RNA polymerase II promoter; IEA:InterPro.
DR   CDD; cd08050; TAF6C; 1.
DR   Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR   Gene3D; 1.25.40.770; TAF6, C-terminal HEAT repeat domain; 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR009072; Histone-fold.
DR   InterPro; IPR037796; TAF6.
DR   InterPro; IPR011442; TAF6_C.
DR   InterPro; IPR046344; TAF6_C_sf.
DR   InterPro; IPR004823; TAF_TATA-bd_Histone-like_dom.
DR   PANTHER; PTHR10221; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6; 1.
DR   PANTHER; PTHR10221:SF9; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6; 1.
DR   Pfam; PF02969; TAF; 1.
DR   Pfam; PF07571; TAF6_C; 1.
DR   SMART; SM00803; TAF; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF47113; Histone-fold; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          11..75
FT                   /note="TATA box binding protein associated factor (TAF)
FT                   histone-like fold"
FT                   /evidence="ECO:0000259|SMART:SM00803"
FT   REGION          455..511
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          544..569
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          638..662
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        462..511
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   662 AA;  71286 MW;  413CD4C4FCCD5EC8 CRC64;
     MGDRDKTMYG STLSLESMKV IAESIGVGSL PDDAAKELAD DVSFKLKQIV QDAVKFMHHS
     KRMKLSIADV DHSLKVRNIE PQYGFVARDF IPFRFASGGG RELHFIEEKE VDLTEVVQGQ
     PPKIPLEPSL RTHWLAVEGV QPTVPENPPP LSKDVQALDS VNPAHKLDKT NRKDTTGKPT
     INKHKLKNSE TVQVKQLAQH ELSVEQQLYY KEITEACVGS DEARRAEALT SLSSDPGLHE
     MLPRMCTFIA EGVKVNVVQN NLALLIYLMR MVRALLDNPA LYLEKYLHEL IPCVSTCIVS
     RQLCMRPELD NHWALRDFAA RLMAQICKTF NTSTNNLQTR VTRLFSAALQ NDKTPLSSMY
     GALQGLSELG TEVTKVFIIP RLKFISERVE PLLQGITSNI SNTDKIAAGH IRAMLLKGVP
     PILKTLRNPP DLVEEYKRDY GCLGQTLHQA VVKARSASPS AGAPGSGGSS ISTTTPSATT
     SITVSTSSNS SNTVVLTSAP SSRPQTPQSS VAKTMAATAS IQRPGTVTGV ATQPQQKFVI
     VPQRTQTPSP SQGPIIQRQS SSVSSGGASI ATPNTVQLQT IKLEPGTLTA AGAVQPSAGV
     GGTTAIGQKV VIINQSQAGP AANIITKPNA FIAAGTGGGN GQEMPDDIIQ VPPELDDLSH
     LE
//