ID A0A182SPS7_9DIPT Unreviewed; 726 AA.
AC A0A182SPS7;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Rab-GAP TBC domain-containing protein {ECO:0000313|EnsemblMetazoa:AMAM010992-PA};
OS Anopheles maculatus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles; Anopheles maculatus group.
OX NCBI_TaxID=74869 {ECO:0000313|EnsemblMetazoa:AMAM010992-PA, ECO:0000313|Proteomes:UP000075901};
RN [1] {ECO:0000313|Proteomes:UP000075901}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=maculatus3 {ECO:0000313|Proteomes:UP000075901};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles maculatus species B.";
RL Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AMAM010992-PA}
RP IDENTIFICATION.
RC STRAIN=maculatus3 {ECO:0000313|EnsemblMetazoa:AMAM010992-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR AlphaFoldDB; A0A182SPS7; -.
DR EnsemblMetazoa; AMAM010992-RA; AMAM010992-PA; AMAM010992.
DR VEuPathDB; VectorBase:AMAM010992; -.
DR OrthoDB; 3034081at2759; -.
DR Proteomes; UP000075901; Unassembled WGS sequence.
DR CDD; cd13354; PH-GRAM2_TCB1D9_TCB1D9B; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR Gene3D; 1.10.8.270; putative rabgap domain of human tbc1 domain family member 14 like domains; 1.
DR Gene3D; 1.10.472.80; Ypt/Rab-GAP domain of gyp1p, domain 3; 1.
DR InterPro; IPR004182; GRAM.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR000195; Rab-GAP-TBC_dom.
DR InterPro; IPR035969; Rab-GAP_TBC_sf.
DR InterPro; IPR036017; TCB1D9/TCB1D9B_PH-GRAM2.
DR PANTHER; PTHR47219; RAB GTPASE-ACTIVATING PROTEIN 1-LIKE; 1.
DR PANTHER; PTHR47219:SF19; RUN AND TBC1 DOMAIN-CONTAINING PROTEIN 3; 1.
DR Pfam; PF02893; GRAM; 2.
DR Pfam; PF00566; RabGAP-TBC; 1.
DR SMART; SM00568; GRAM; 2.
DR SMART; SM00164; TBC; 1.
DR SUPFAM; SSF47923; Ypt/Rab-GAP domain of gyp1p; 2.
DR PROSITE; PS50086; TBC_RABGAP; 1.
PE 4: Predicted;
FT DOMAIN 426..613
FT /note="Rab-GAP TBC"
FT /evidence="ECO:0000259|PROSITE:PS50086"
SQ SEQUENCE 726 AA; 84536 MW; 0E615D6C3A1D3CC6 CRC64;
MSFRSHAKGT RNFMLPFFLF VCLVTLLLLL FYLEIAADIT LEAIMLDWDW LTKNLFRVIN
EMETEEEITN FTICKIQSLL AHSSRPAEEQ NDPTSFQVAV CKFREKFRMP EDEKLVNYYY
CSYFRKIPRQ GQLYLSLNHI CFYSYILGSE SKLCFRYNEL TDIKKSGNTI TVRAGQQGSK
EYTFVFLYSP SEAYQLIEQL SKLTMQKMIQ DPDRPIVDHD PVILKKMEKN VAQKTLLLRD
LTARQQSDEY RIHFRVPKTE ILDGMIKASL WAPYTKKHIN GVLYLSQNYL CFKGDVTGMV
SLVIPLSKIV SVEKNDDPHN RLSNRIIITT SDGNIFVLKH ILDREFLINK ISELLSKTVP
PASRTHDDLD WIKQEPLMYL YKDPNNRAFD DLQAEKMKRW DEHFSLYGRG ISMYRTTDTI
NLVIEGIPDQ LRREVWLNFS GAVHMKMMQP NLYQQLVAKA KDQSPVSFEE IERDLHRSLP
EHPAFQTSIG ITALRRVLQA YALRNPEIGY CQAMNIVSSV FLIYCDEEDA FWILCCLCES
LLPDYYNDRV VGAQIDQGLL DELIAGHLPN LHVKLTELGM IRMISLSWFL TIFLSVMPYE
SALHIIDCFL CDGAKVIFII ALKILEWNQE KLLNCNDDGE AMQLLSNFLM GIFNDEVQRI
MIEDKEKQQI KSQSVQTLIY EAYLKFGKAI TSQKIEELRN KHRRLTVHQL EKDLENSVIK
NYKDNG
//
