ID A0A182SYI7_9DIPT Unreviewed; 1107 AA.
AC A0A182SYI7;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=ATP-dependent RNA helicase DHX57 {ECO:0008006|Google:ProtNLM};
OS Anopheles maculatus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles; Anopheles maculatus group.
OX NCBI_TaxID=74869 {ECO:0000313|EnsemblMetazoa:AMAM016006-PA, ECO:0000313|Proteomes:UP000075901};
RN [1] {ECO:0000313|Proteomes:UP000075901}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=maculatus3 {ECO:0000313|Proteomes:UP000075901};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles maculatus species B.";
RL Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AMAM016006-PA}
RP IDENTIFICATION.
RC STRAIN=maculatus3 {ECO:0000313|EnsemblMetazoa:AMAM016006-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR AlphaFoldDB; A0A182SYI7; -.
DR EnsemblMetazoa; AMAM016006-RA; AMAM016006-PA; AMAM016006.
DR VEuPathDB; VectorBase:AMAM016006; -.
DR OrthoDB; 1095660at2759; -.
DR Proteomes; UP000075901; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR Gene3D; 4.10.1000.10; Zinc finger, CCCH-type; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR006575; RWD_dom.
DR InterPro; IPR015940; UBA.
DR InterPro; IPR009060; UBA-like_sf.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR InterPro; IPR041367; Znf-CCCH_4.
DR InterPro; IPR000571; Znf_CCCH.
DR InterPro; IPR036855; Znf_CCCH_sf.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF145; ATP-DEPENDENT RNA HELICASE DHX29; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF05773; RWD; 1.
DR Pfam; PF18044; zf-CCCH_4; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF90229; CCCH zinc finger; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR SUPFAM; SSF54495; UBC-like; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50030; UBA; 1.
DR PROSITE; PS50103; ZF_C3H1; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00723}; Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00723};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00723}.
FT DOMAIN 54..99
FT /note="UBA"
FT /evidence="ECO:0000259|PROSITE:PS50030"
FT DOMAIN 191..218
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT DOMAIN 407..581
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 678..859
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT ZN_FING 191..218
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT REGION 162..181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1107 AA; 126307 MW; 40950959C8BBEAAA CRC64;
METLRAIHGE AFQLGDISKY EDKGGRMKKG FWQDRGNLVI QGGVDFSNIP RTGNTNEDKF
RMYAVMKLHS YAFHRAHCEE ALDHHNGDVD SALALLFSKY FPPPNNLQPP VEDHNEDELT
ALRADEREVL ESIYDKLFVE KEHNRVWQLK FKIDHLLTHS PSEMRKQAER EAQQAEEEKR
RMQEALAKKK KAKREKCWNF AKGKCRYGNR CHYSHELDES DSEEKKNSKK VEKTMEEDPN
WFFLEIRFPP GNRYPFERPI LLLKTTCSDI PEQLCLRVNR RLVQECIELT NDGMPCIYAV
ADLLQNDEEI GRFIEQDRYQ FPDGRRSLFY VPEQDAIEVG MGNNLPTHHQ RGVTGRQTGT
KINPEQVMKE DRNIVRKFMD KQTNEAYKEM LKNRRKLPAW TKMAEIINLM ESHQILVISG
ETGCGKSTQV PQFLLDDWLL QSSKVQSKDP LRHVEIICTQ PRRLSAIGVA ERVAEERNEK
IGNTVGYQIR LENKISSSTR LTFCTTGILL RRLQSDPVLA SVTHIIVDEV HERSEESDFL
LLILKELMGK RTDLKVILMS ATLNSNLFSS YFGDIPVLDI PGRTFPVEQL FLEDILDRSG
FVLEPDSQFC RKLRKGEHEQ LLQELEYSDV QAANAAPAKT IRDENLKMAD LFARYAEYSK
QTCKALYLMD PLRINPELIE HVLTYIVDDS SHSWPKEGSI LIFLPGLAEI QTVHESLADS
KLFGARGDRF VLIPLHSMLT NEEQALVFRK APKGKRKIVL STNIAETSVT IDDCVFVLDC
GQMKEKRFDS NRNMESLEMV WVSRANALQR KGRAGRVMPG VCIHLYTRPR FTHHILGQPV
PEIHRIPLEP LLLRVKTLAT FEERSVNGVL GALIEPPSVE NIQAAKKRLV DVGALDLEEQ
LTPLGHHLSA LPVDVRIGKL MLFGAIFQCL DSVLTVAAIL SYKSPFVSPF GKRDEADNRK
RQFAIANSDH LTMLNAYRRW MEAAQKSRYA GQCFAEQNYL SGKTLATIGE MKYQFLELLV
SIGFVPLDLS GRSRAKRQQL DELPKLTGPE INVNGSNNRL LAAILCAALY PNVVKILTPE
KSFVTGAVGA VPRLPQASDL RFKTQAD
//
