ID   A0A182T2T1_9DIPT        Unreviewed;       351 AA.
AC   A0A182T2T1;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   RecName: Full=PX domain-containing protein {ECO:0000259|PROSITE:PS50195};
OS   Anopheles maculatus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles; Anopheles maculatus group.
OX   NCBI_TaxID=74869 {ECO:0000313|EnsemblMetazoa:AMAM018454-PA, ECO:0000313|Proteomes:UP000075901};
RN   [1] {ECO:0000313|Proteomes:UP000075901}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=maculatus3 {ECO:0000313|Proteomes:UP000075901};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles maculatus species B.";
RL   Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AMAM018454-PA}
RP   IDENTIFICATION.
RC   STRAIN=maculatus3 {ECO:0000313|EnsemblMetazoa:AMAM018454-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the sorting nexin family.
CC       {ECO:0000256|ARBA:ARBA00010883}.
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DR   AlphaFoldDB; A0A182T2T1; -.
DR   EnsemblMetazoa; AMAM018454-RA; AMAM018454-PA; AMAM018454.
DR   VEuPathDB; VectorBase:AMAM018454; -.
DR   OrthoDB; 5398040at2759; -.
DR   Proteomes; UP000075901; Unassembled WGS sequence.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   CDD; cd06892; PX_SNX5_like; 1.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR001683; PX_dom.
DR   InterPro; IPR036871; PX_dom_sf.
DR   InterPro; IPR015404; Vps5_C.
DR   PANTHER; PTHR45850:SF1; SORTING NEXIN 6, ISOFORM B; 1.
DR   PANTHER; PTHR45850; SORTING NEXIN FAMILY MEMBER; 1.
DR   Pfam; PF00787; PX; 1.
DR   Pfam; PF09325; Vps5; 1.
DR   SUPFAM; SSF64268; PX domain; 1.
DR   PROSITE; PS50195; PX; 1.
PE   3: Inferred from homology;
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          32..179
FT                   /note="PX"
FT                   /evidence="ECO:0000259|PROSITE:PS50195"
SQ   SEQUENCE   351 AA;  39796 MW;  926A91C927F66E17 CRC64;
     NVTSPAAPAE SIAVSRQGSI EGGGSTTASI GALPENSLLV DISDALSEKE RVKFTVHTRT
     NLPGFEKPDF LVVRQHEEFV WLHERFEENE EYAGYIIPPC PPRPDFDASR EKLQRLGEGE
     GNMTKEEFKK MKQELEAEYL ATFKKTVAMH EVFLTRLASH PVFREDSHLK VFLVYDQDLC
     AKMKKKIDIF GGLVKSIGKT TDEIYLGATV KDVNDFFEHE LQFLGEYHGH LKEAAIRTEK
     MTNKHKDVAD SHVRISSQLL ALSTAEHHGS MEKFLAKTSD IFEKIRNMEG RVASDQDLKL
     GDTLRYYQRD SNAAKALLIR RLRCLAAYEA ANRNLEKARA KNKDVHAVRI F
//