ID   A0A182TGG1_9DIPT        Unreviewed;       635 AA.
AC   A0A182TGG1;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=Sema domain-containing protein {ECO:0000259|PROSITE:PS51004};
OS   Anopheles melas.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=34690 {ECO:0000313|EnsemblMetazoa:AMEC001876-PA, ECO:0000313|Proteomes:UP000075902};
RN   [1] {ECO:0000313|Proteomes:UP000075902}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CM1001059 {ECO:0000313|Proteomes:UP000075902};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles melas CM1001059_A (V2).";
RL   Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AMEC001876-PA}
RP   IDENTIFICATION.
RC   STRAIN=CM1001059 {ECO:0000313|EnsemblMetazoa:AMEC001876-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR   AlphaFoldDB; A0A182TGG1; -.
DR   STRING; 34690.A0A182TGG1; -.
DR   EnsemblMetazoa; AMEC001876-RA; AMEC001876-PA; AMEC001876.
DR   VEuPathDB; VectorBase:AMEC001876; -.
DR   Proteomes; UP000075902; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0017154; F:semaphorin receptor activity; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   CDD; cd11236; Sema_plexin_like; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR031148; Plexin.
DR   InterPro; IPR002165; Plexin_repeat.
DR   InterPro; IPR016201; PSI.
DR   InterPro; IPR001627; Semap_dom.
DR   InterPro; IPR036352; Semap_dom_sf.
DR   InterPro; IPR041019; TIG1_plexin.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR22625; PLEXIN; 1.
DR   PANTHER; PTHR22625:SF69; PLEXIN A, ISOFORM A; 1.
DR   Pfam; PF01437; PSI; 1.
DR   Pfam; PF01403; Sema; 1.
DR   Pfam; PF17960; TIG_plexin; 1.
DR   SMART; SM00423; PSI; 1.
DR   SMART; SM00630; Sema; 1.
DR   SUPFAM; SSF103575; Plexin repeat; 1.
DR   SUPFAM; SSF101912; Sema domain; 1.
DR   PROSITE; PS51004; SEMA; 1.
PE   4: Predicted;
KW   Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Neurogenesis {ECO:0000256|ARBA:ARBA00022902}.
FT   DOMAIN          27..488
FT                   /note="Sema"
FT                   /evidence="ECO:0000259|PROSITE:PS51004"
SQ   SEQUENCE   635 AA;  69581 MW;  5DAE3E18E10E1BDE CRC64;
     MYGGAMVEGG KGSASIAMER FQRTGTALLI LISVLCAQPQ ANHNVPSKGS NATDLSSRLV
     YVGAVNKLYQ ISNELNILTV VTTGPQNDSY QCTILECPGG AVKTPMDNVN KMLLIDSNAK
     NLIVCGSLFQ GICHIRNLHN ISIVEQEVLE AVVANTANAS TVAFIAPGPP LASAENNVLY
     VAVTFTGNSP YRSEIPAVSS RSLARDRLFQ LAASAVTTGT RLFVNNYARE TYIINYVYGF
     SSERFSYFLT TQYKSSSHYA SKERITKLVR ICQDDSHYHS YTEIPVDCTS KDGTKFKTVS
     AAYVGKPGHE LAQSLEITTN DDVLFAVFDA PTANKSALCV YSLKAIRKKF MHNIKKCYNG
     EGLRGLDYIS QNMPCIATKL QTIGEDFCGL DVNSPLGGEQ AVASLAVILS EERMTSVAVT
     ATSNFTVVFI GTETGQLKKI VMESSTSAMQ YAMMNVDLGS PIQPDMYLDP EHDDLYLMSL
     YKLFKIRIYD CSVYTTCHAC LSAKDPFCGW CSLENKCSRR YECQDSSKDP LSWLSYKSGK
     CTTITSVTPH QLQRTTARTL ELIIENLPNL KEPLVCAFTF ASMEKPIITN ATKKRNGVNC
     TTPRTDLLPQ IGYGENHFNA TLSIKTSQGP DIVST
//