ID A0A182TN23_9DIPT Unreviewed; 684 AA.
AC A0A182TN23;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=USP domain-containing protein {ECO:0000259|PROSITE:PS50235};
OS Anopheles melas.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=34690 {ECO:0000313|EnsemblMetazoa:AMEC005299-PA, ECO:0000313|Proteomes:UP000075902};
RN [1] {ECO:0000313|Proteomes:UP000075902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CM1001059 {ECO:0000313|Proteomes:UP000075902};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles melas CM1001059_A (V2).";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AMEC005299-PA}
RP IDENTIFICATION.
RC STRAIN=CM1001059 {ECO:0000313|EnsemblMetazoa:AMEC005299-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR AlphaFoldDB; A0A182TN23; -.
DR STRING; 34690.A0A182TN23; -.
DR EnsemblMetazoa; AMEC005299-RA; AMEC005299-PA; AMEC005299.
DR VEuPathDB; VectorBase:AMEC005299; -.
DR Proteomes; UP000075902; Unassembled WGS sequence.
DR GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR001394; Peptidase_C19_UCH.
DR InterPro; IPR018200; USP_CS.
DR InterPro; IPR028889; USP_dom.
DR PANTHER; PTHR24006; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR PANTHER; PTHR24006:SF702; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 47; 1.
DR Pfam; PF00443; UCH; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00973; USP_2; 1.
DR PROSITE; PS50235; USP_3; 1.
PE 4: Predicted;
FT DOMAIN 1..233
FT /note="USP"
FT /evidence="ECO:0000259|PROSITE:PS50235"
FT REGION 85..147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 520..540
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 565..605
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 629..655
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 85..122
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 565..594
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 684 AA; 75270 MW; 45B05F14C0D01DA0 CRC64;
FPYILTLHLK RFDFDYQSFH RIKLNDKVTF PELLNLNHFV SSTPTLTTST IAAAAAAAAA
AASTTNGTAN GNGPMMMETA ENFMKSDECS TTDSGSALEE DSFQNGGTSV SSTTTTPNDQ
FMAQDDDEGI DMDLTTNGDS KSSPVNNSFN APGPYKYELF AIMIHAGSAS GGHYYAYIKD
FKSGRWFSFN DQTVLPITQE DIHKSYGGGS YKTSYTGAYT SSTNAYMLMY RQIDSEKNAL
PISEEQFPDH IKRLVMKIRA NEGNHSRDHL DMTRLTVAYE NPRTRTIKGH KMAVFTSSTL
AETVQEAVRV LHLKGTVPVE RCRLVGYDCN ARTIERSFEG HEEKTIDEVM RMLKRCDSLL
LEVREEGETF EEYQVQGVMT KVYKVDVNGR DVEGPVSIRA NLSQTVAQYR AIIARKLKLN
PKAILVGMTV QKESAKLLQT DDATLEDEHF IEYCKVFVTV APTAGDDREQ YGARFRHFIQ
RLDHLVSFYI VLPNMDPDTL ESLSIPRLSK ETLAAIAAAD SPMAGGTGDS NSEDSSLSDN
DRTLVEDDFV HIKLNGDLHL TNGGSSGAGA MSNGTAAKGS SKATATTPTS ASNGFKSDEE
EDEDAKLAEM LQECRAQEYY FKVTPLNTAS SSSNGASNGS SADDSTRSHS TDSGSQKLVQ
VLIDKRSCNA YLKYRLQSYL QISM
//
