ID A0A182TWT6_9DIPT Unreviewed; 388 AA.
AC A0A182TWT6;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 28-JUN-2023, entry version 23.
DE RecName: Full=V-type proton ATPase subunit S1/VOA1 transmembrane domain-containing protein {ECO:0000259|Pfam:PF20520};
OS Anopheles melas.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=34690 {ECO:0000313|EnsemblMetazoa:AMEC009734-PA, ECO:0000313|Proteomes:UP000075902};
RN [1] {ECO:0000313|Proteomes:UP000075902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CM1001059 {ECO:0000313|Proteomes:UP000075902};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles melas CM1001059_A (V2).";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AMEC009734-PA}
RP IDENTIFICATION.
RC STRAIN=CM1001059 {ECO:0000313|EnsemblMetazoa:AMEC009734-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the vacuolar ATPase subunit S1 family.
CC {ECO:0000256|ARBA:ARBA00009037}.
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DR AlphaFoldDB; A0A182TWT6; -.
DR STRING; 34690.A0A182TWT6; -.
DR EnsemblMetazoa; AMEC009734-RA; AMEC009734-PA; AMEC009734.
DR VEuPathDB; VectorBase:AMEC009734; -.
DR Proteomes; UP000075902; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR008388; Ac45_acc_su.
DR InterPro; IPR046756; VAS1/VOA1_TM.
DR PANTHER; PTHR12471:SF7; V-TYPE PROTON ATPASE SUBUNIT S1; 1.
DR PANTHER; PTHR12471; VACUOLAR ATP SYNTHASE SUBUNIT S1; 1.
DR Pfam; PF20520; Ac45-VOA1_TM; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..388
FT /note="V-type proton ATPase subunit S1/VOA1 transmembrane
FT domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008137406"
FT TRANSMEM 344..363
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 338..376
FT /note="V-type proton ATPase subunit S1/VOA1 transmembrane"
FT /evidence="ECO:0000259|Pfam:PF20520"
SQ SEQUENCE 388 AA; 43083 MW; B714AB6B0A3D7ACF CRC64;
MVKLGVTVTL FLALAVFGSA RAANVPVFVW GKPSVTYVPA LSLYSSSEFG ALVEAQIDEK
TFTIVFAEDR LSAEDLSQCK LKTQTCFKNL QKLERKSYLP SVEEPLSVLE GSNAQSVQLR
PDGTLSERIV PQAGGIVVVN LSGDDFASHD ALIDALYARL HKEHPNIVAI YTGKTPSFSY
SSLVRKTRQA GQEPEPAKVE LKTDGFLMVY EKFMFGQADA AELTVAQLGQ ATKVENATTD
VVQIRLTGAG AQVDLFFLLT QGSWEITGVW FDNQEYYLRH RVHVSQHFSY SCNQWEYYSY
DLQKKIVFEE VQLQPFWPGA DGVAPPNNRF GDAWYCVGFT TGGILSGLFL VLIFIIIGSY
GIAWMMDIRT MDRFDDPKGK TITVNAAE
//
