ID   A0A182TXX6_9DIPT        Unreviewed;       826 AA.
AC   A0A182TXX6;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=F-actin binding domain-containing protein {ECO:0000259|SMART:SM00808};
OS   Anopheles melas.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=34690 {ECO:0000313|EnsemblMetazoa:AMEC010316-PA, ECO:0000313|Proteomes:UP000075902};
RN   [1] {ECO:0000313|Proteomes:UP000075902}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CM1001059 {ECO:0000313|Proteomes:UP000075902};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles melas CM1001059_A (V2).";
RL   Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AMEC010316-PA}
RP   IDENTIFICATION.
RC   STRAIN=CM1001059 {ECO:0000313|EnsemblMetazoa:AMEC010316-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
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DR   AlphaFoldDB; A0A182TXX6; -.
DR   STRING; 34690.A0A182TXX6; -.
DR   EnsemblMetazoa; AMEC010316-RA; AMEC010316-PA; AMEC010316.
DR   VEuPathDB; VectorBase:AMEC010316; -.
DR   Proteomes; UP000075902; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:InterPro.
DR   Gene3D; 1.20.120.330; Nucleotidyltransferases domain 2; 1.
DR   InterPro; IPR015015; F-actin-binding.
DR   Pfam; PF08919; F_actin_bind; 1.
DR   SMART; SM00808; FABD; 1.
PE   4: Predicted;
FT   DOMAIN          702..826
FT                   /note="F-actin binding"
FT                   /evidence="ECO:0000259|SMART:SM00808"
FT   REGION          94..293
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          322..461
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          519..558
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          598..648
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          699..721
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        95..113
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        135..149
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        161..175
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        255..293
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        323..356
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        357..430
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        445..461
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        528..542
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        609..643
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   826 AA;  86342 MW;  B9FD8414D502446C CRC64;
     MTLVSEPPPP PMAAANAISN SILAQRNAAA IKAQPQMIRS NSSSGVTMSN SATASLSKLQ
     RHRTTTDGSM MTFSSFRGSV GNNSPKRAVQ PTLADLEFPP PPVDLPPPPE EFDMPLDQRG
     GGGGSGGMLE KSIAPSNDVR NTEPSVEEAS TRFGVSLRKR EPSTDSCSSL GSPADAMINT
     VGDPSSLPIP PPPPSKDLKA DPKRVTNVPK CLQGDVVGGK RTAGPLHGTS DPASQLVSEL
     AESMQLPKAP SPLTIAQEPQ HQQQQQQPIS HYKSSDISSL RKPVSMSKST ILPSTNAAAN
     DNYSAATNAA SGLPQPPFKA QLKKVDTAKR APAQPAKKEE STGGIIDFKS RLRKVDQNNT
     EVSSNGGSGG GESVDPPTSN VDNNNKHQAG GNSLQSIHNN NLNTTASSNN SNGNILNNND
     NSASSSSSEN ENHRSAKKGE TGTPMVVRNG TSISGKNSMD SSNKLLLENN ELNSLKLKKT
     NVASTIVTGT APIDSNKVIE LKKTEIKIEL SDDRKRESLE GNSLKVDSGG GSGDNLSTGS
     SGAGGEDGDG KRKSTGSISS LKKLWEAKES PSDPLSAQLS PKLGTKSVAN MVPKMNNNVE
     AEDGSVGGGH DATQQQQQQQ EQQLQQATAG PAGCVSTGTL GSNKKPAVPM KPSKFSSIYA
     TPVQNMMQTA SSTVASATGS SVGGGGTSNT SNIYAKSNDS SSIIQQSDKP ASTTGSATSS
     AGGRESILEL VQLLQTSLKQ PVGNISASQW LALSDRLNSL QSSCVTFADN ESLPPHAKFH
     FRELVTRVEN QARSLRSASN KNVQDNEKLV QEVGQSLKQI SNALHR
//