ID   A0A182U016_9DIPT        Unreviewed;       180 AA.
AC   A0A182U016;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   13-SEP-2023, entry version 31.
DE   RecName: Full=60S ribosome subunit biogenesis protein NIP7 homolog {ECO:0000256|ARBA:ARBA00018162, ECO:0000256|PIRNR:PIRNR017190};
OS   Anopheles melas.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=34690 {ECO:0000313|EnsemblMetazoa:AMEC011441-PA, ECO:0000313|Proteomes:UP000075902};
RN   [1] {ECO:0000313|EnsemblMetazoa:AMEC011441-PA, ECO:0000313|Proteomes:UP000075902}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CM1001059 {ECO:0000313|EnsemblMetazoa:AMEC011441-PA,
RC   ECO:0000313|Proteomes:UP000075902};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles melas CM1001059_A (V2).";
RL   Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AMEC011441-PA}
RP   IDENTIFICATION.
RC   STRAIN=CM1001059 {ECO:0000313|EnsemblMetazoa:AMEC011441-PA};
RG   VectorBase;
RL   Submitted (JUN-2016) to UniProtKB.
RN   [3] {ECO:0000313|EnsemblMetazoa:AMEC011441-PA}
RP   IDENTIFICATION.
RC   STRAIN=CM1001059 {ECO:0000313|EnsemblMetazoa:AMEC011441-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAR-2023) to UniProtKB.
CC   -!- FUNCTION: Required for proper 34S pre-rRNA processing and 60S ribosome
CC       subunit assembly. {ECO:0000256|ARBA:ARBA00004087,
CC       ECO:0000256|PIRNR:PIRNR017190}.
CC   -!- SUBUNIT: Interacts with pre-ribosome complex.
CC       {ECO:0000256|PIRNR:PIRNR017190}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000256|ARBA:ARBA00004604}.
CC   -!- SIMILARITY: Belongs to the NIP7 family. {ECO:0000256|ARBA:ARBA00009895,
CC       ECO:0000256|PIRNR:PIRNR017190}.
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DR   AlphaFoldDB; A0A182U016; -.
DR   STRING; 34690.A0A182U016; -.
DR   EnsemblMetazoa; AMEC011441-RA; AMEC011441-PA; AMEC011441.
DR   VEuPathDB; VectorBase:AMEC011441; -.
DR   Proteomes; UP000075902; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042255; P:ribosome assembly; IEA:InterPro.
DR   CDD; cd21146; Nip7_N_euk; 1.
DR   CDD; cd21151; PUA_Nip7-like; 1.
DR   Gene3D; 3.10.450.220; -; 1.
DR   Gene3D; 2.30.130.10; PUA domain; 1.
DR   InterPro; IPR040598; NIP7_N.
DR   InterPro; IPR002478; PUA.
DR   InterPro; IPR015947; PUA-like_sf.
DR   InterPro; IPR036974; PUA_sf.
DR   InterPro; IPR016686; Ribosomal_synth_fac_NIP7.
DR   InterPro; IPR005155; UPF0113_PUA.
DR   PANTHER; PTHR23415:SF4; 60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 HOMOLOG; 1.
DR   PANTHER; PTHR23415; CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7; 1.
DR   Pfam; PF03657; UPF0113; 1.
DR   Pfam; PF17833; UPF0113_N; 1.
DR   PIRSF; PIRSF017190; Rbsml_synth_fac_NIP7; 1.
DR   SMART; SM00359; PUA; 1.
DR   SUPFAM; SSF88802; Pre-PUA domain; 1.
DR   SUPFAM; SSF88697; PUA domain-like; 1.
DR   PROSITE; PS50890; PUA; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR017190};
KW   Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517,
KW   ECO:0000256|PIRNR:PIRNR017190};
KW   RNA-binding {ECO:0000256|PIRNR:PIRNR017190}.
FT   DOMAIN          95..170
FT                   /note="PUA"
FT                   /evidence="ECO:0000259|SMART:SM00359"
SQ   SEQUENCE   180 AA;  20342 MW;  2C5ACDBBC0A2F708 CRC64;
     MKRLSEQQTK VLFEKLSKYI GTNVKLLIDR SDGTYCFREM KSRVYYMSEK ILKLAETVPK
     EHMVSVGTCF GKFTKGNKFI LHITALTYLA PYAQYKIWLK PAAEQQFLYG NNVAKSGMGR
     ITENTPVYQG VIVMSMSDVP LGFGVAAKST NDCKLADPLV TVCFHQADIG EYIRSEENLI
//