ID A0A182U5H5_9DIPT Unreviewed; 268 AA.
AC A0A182U5H5;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=DH domain-containing protein {ECO:0000259|PROSITE:PS50010};
OS Anopheles melas.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=34690 {ECO:0000313|EnsemblMetazoa:AMEC014256-PA, ECO:0000313|Proteomes:UP000075902};
RN [1] {ECO:0000313|Proteomes:UP000075902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CM1001059 {ECO:0000313|Proteomes:UP000075902};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles melas CM1001059_A (V2).";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AMEC014256-PA}
RP IDENTIFICATION.
RC STRAIN=CM1001059 {ECO:0000313|EnsemblMetazoa:AMEC014256-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A182U5H5; -.
DR STRING; 34690.A0A182U5H5; -.
DR EnsemblMetazoa; AMEC014256-RA; AMEC014256-PA; AMEC014256.
DR VEuPathDB; VectorBase:AMEC014256; -.
DR Proteomes; UP000075902; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR PANTHER; PTHR22826; RHO GUANINE EXCHANGE FACTOR-RELATED; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR PROSITE; PS50010; DH_2; 1.
PE 4: Predicted;
FT DOMAIN 139..244
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT REGION 40..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 268 AA; 30708 MW; 93DCFE7FE6E51FAD CRC64;
MYDILVVNKN YDAEGPDSIS VRVGDLVEVL DMGDSAVNAA KKPKLDPQMN IGQSEDRLDS
SASRHKLAVK PKKNHQSSSH RRSVSPQPPY QPKPNEKWKV RIFDGDDNAK AGWIPVSVLD
INHTEQAVFG EKSNDAAYRR EAVVRELVET EEEFAKDLQQ VVDNYLKYID NKDNKVPRVV
RDHKDDIFNN FKQIADFHNT VLIEGVKYYA NNPKMIGKTF LRLERDFDKH VKYCRDAPVA
QEFLASNDAI RDFFMVRNMI GILLNCIN
//
