ID   A0A182U7I6_9DIPT        Unreviewed;       331 AA.
AC   A0A182U7I6;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Tropomyosin {ECO:0008006|Google:ProtNLM};
OS   Anopheles melas.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=34690 {ECO:0000313|EnsemblMetazoa:AMEC015326-PA, ECO:0000313|Proteomes:UP000075902};
RN   [1] {ECO:0000313|Proteomes:UP000075902}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CM1001059 {ECO:0000313|Proteomes:UP000075902};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles melas CM1001059_A (V2).";
RL   Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AMEC015326-PA}
RP   IDENTIFICATION.
RC   STRAIN=CM1001059 {ECO:0000313|EnsemblMetazoa:AMEC015326-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- FUNCTION: Tropomyosin, in association with the troponin complex, plays
CC       a central role in the calcium dependent regulation of muscle
CC       contraction. {ECO:0000256|ARBA:ARBA00002987}.
CC   -!- SIMILARITY: Belongs to the tropomyosin family.
CC       {ECO:0000256|ARBA:ARBA00009036}.
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DR   AlphaFoldDB; A0A182U7I6; -.
DR   STRING; 34690.A0A182U7I6; -.
DR   EnsemblMetazoa; AMEC015326-RA; AMEC015326-PA; AMEC015326.
DR   VEuPathDB; VectorBase:AMEC015326; -.
DR   Proteomes; UP000075902; Unassembled WGS sequence.
DR   Gene3D; 1.20.5.170; -; 1.
DR   InterPro; IPR000533; Tropomyosin.
DR   PANTHER; PTHR19269; TROPOMYOSIN; 1.
DR   PANTHER; PTHR19269:SF45; TROPOMYOSIN-1, ISOFORMS 33_34; 1.
DR   Pfam; PF00261; Tropomyosin; 1.
DR   PRINTS; PR00194; TROPOMYOSIN.
DR   SUPFAM; SSF57997; Tropomyosin; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils}.
FT   REGION          156..331
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          22..134
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        162..185
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   331 AA;  34393 MW;  85973EE94D595DFE CRC64;
     MPTAVLTLGD AFPTPDALVA ELDQVARKLV LMEQDLERSE EKVEMNESKI VELEEELRVV
     GNNLKSLEVS EEKANQREEE YKNQIKTLTT RLKEAMASRD SVEDKIHQLN DKLTNKLQKE
     VDRLEDELIV EKLRYAEIGD DLDFAFVDLI PGIDPIWTER RPKPKTPPPP PKLPTPPPPP
     PAPKEEAAAA AGGEGEGAAA GGEGAPAGPT KARTPSPFEL RKHFPPEAAE VPYVRSSTGT
     TPKSSPAKEV APAEAAAAPA PEAAAPAEAP AEGGADAAAP PAEAAAPAAE GDAPAAPAAE
     GEAAAPAPEA AAPAAEAAPP AAEPAPEAPA S
//