ID A0A182U9G6_9DIPT Unreviewed; 427 AA.
AC A0A182U9G6;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Solute carrier family 25 member 46 {ECO:0008006|Google:ProtNLM};
OS Anopheles melas.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=34690 {ECO:0000313|EnsemblMetazoa:AMEC016374-PA, ECO:0000313|Proteomes:UP000075902};
RN [1] {ECO:0000313|Proteomes:UP000075902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CM1001059 {ECO:0000313|Proteomes:UP000075902};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles melas CM1001059_A (V2).";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AMEC016374-PA}
RP IDENTIFICATION.
RC STRAIN=CM1001059 {ECO:0000313|EnsemblMetazoa:AMEC016374-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC outer membrane {ECO:0000256|ARBA:ARBA00004374}; Multi-pass membrane
CC protein {ECO:0000256|ARBA:ARBA00004374}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000256|ARBA:ARBA00006375, ECO:0000256|RuleBase:RU000488}.
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DR AlphaFoldDB; A0A182U9G6; -.
DR STRING; 34690.A0A182U9G6; -.
DR EnsemblMetazoa; AMEC016374-RA; AMEC016374-PA; AMEC016374.
DR VEuPathDB; VectorBase:AMEC016374; -.
DR Proteomes; UP000075902; Unassembled WGS sequence.
DR GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0090149; P:mitochondrial membrane fission; IEA:InterPro.
DR Gene3D; 1.50.40.10; Mitochondrial carrier domain; 1.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR InterPro; IPR039158; SLC25A46.
DR PANTHER; PTHR21252:SF2; MITOCHONDRIAL OUTER MEMBRANE PROTEIN SLC25A46; 1.
DR PANTHER; PTHR21252; TB1 PROTEIN-RELATED; 1.
DR Pfam; PF00153; Mito_carr; 1.
DR SUPFAM; SSF103506; Mitochondrial carrier; 1.
DR PROSITE; PS50920; SOLCAR; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Mitochondrion {ECO:0000256|ARBA:ARBA00022787};
KW Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00022787};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Transport {ECO:0000256|RuleBase:RU000488}.
FT REPEAT 281..383
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
SQ SEQUENCE 427 AA; 47941 MW; 8A4CFCCE9DF63A2E CRC64;
MAGLEDYGRY LEDEDELDNA RFLSAYKSTL DDAPYQFINS ERDLTLPLQK HKNVQPLYES
PDDEISLRKY LGASVNLISL ITENLLCHPF LVLRRQCQVH HTARRYHVVP ITLLPVIVHL
HQRQGVTTLW KGIGSVLLVR GMTLAVEDVI SKFTPWPKEI NAKTTVKQFG QHLLLKCISI
AAVVPFYSAS LVETVQSDIA SEKPGIFDVF REGASRLLSW SVPQKGRMLP VWALVGPSIT
LGLSKYVCQL FVRGISTRIM CRRVTFYEER RGARTRDFAA QSQVIEVYST MISLMATEMI
FYPFETILHR IQLQGTRTII DNLDSGYSVV PILTSYEGVV DCYRQTLASE GVSGLYKGFG
AMMLQFAAHV AVIKLGKWFI TQISELMSSK PPAKVVEFYK LEGKTPVGSA TMSRSISGIS
SLSEEIS
//
