ID   A0A182UBF9_9DIPT        Unreviewed;       591 AA.
AC   A0A182UBF9;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   13-SEP-2023, entry version 29.
DE   RecName: Full=BRCA1-associated protein {ECO:0008006|Google:ProtNLM};
OS   Anopheles melas.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=34690 {ECO:0000313|EnsemblMetazoa:AMEC017374-PA, ECO:0000313|Proteomes:UP000075902};
RN   [1] {ECO:0000313|Proteomes:UP000075902}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CM1001059 {ECO:0000313|Proteomes:UP000075902};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles melas CM1001059_A (V2).";
RL   Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AMEC017374-PA}
RP   IDENTIFICATION.
RC   STRAIN=CM1001059 {ECO:0000313|EnsemblMetazoa:AMEC017374-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A182UBF9; -.
DR   STRING; 34690.A0A182UBF9; -.
DR   EnsemblMetazoa; AMEC017374-RA; AMEC017374-PA; AMEC017374.
DR   VEuPathDB; VectorBase:AMEC017374; -.
DR   Proteomes; UP000075902; Unassembled WGS sequence.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd16457; RING-H2_BRAP2; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR   InterPro; IPR011422; BRAP2/ETP1_RRM.
DR   InterPro; IPR047243; RING-H2_BRAP2.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR001607; Znf_UBP.
DR   PANTHER; PTHR24007; BRCA1-ASSOCIATED PROTEIN; 1.
DR   PANTHER; PTHR24007:SF7; BRCA1-ASSOCIATED PROTEIN; 1.
DR   Pfam; PF07576; BRAP2; 1.
DR   Pfam; PF13639; zf-RING_2; 1.
DR   Pfam; PF02148; zf-UBP; 1.
DR   SMART; SM00184; RING; 1.
DR   SMART; SM00290; ZnF_UBP; 1.
DR   SUPFAM; SSF90257; Myosin rod fragments; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
DR   PROSITE; PS50271; ZF_UBP; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00502}.
FT   DOMAIN          262..302
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   DOMAIN          296..391
FT                   /note="UBP-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50271"
FT   REGION          52..72
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          85..115
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          570..591
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          436..477
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   591 AA;  65109 MW;  ACF66E209FFA9CC0 CRC64;
     MSALVSLCLL KIELVADRSR SQSTVMLGPS ESGSACDDAA TGGSIVGDEA AGAVSNEHPN
     NPRLQREMRG QRKPKKITIE SYRNRLLDGG PAPSDEYRGI LPKSSREQTP MDEVPPPAAT
     EILGEINFFS GNPFVEVTKG ILHLFKRNER ADISEGGVSK TLCLIAVPSS LNCHDILNFI
     APCQKEIQHV RILRDGSPNQ FMVLLEFRCV EGAIEFFKTF NGAPYNSLEP DTLCHAVWVS
     SVEWGLDDCC VTPQGHTELP SCPVCLERMD ESVDGVLTIL CNHVFHAGCL NKWGDSTCPV
     CRCVQTPELS EQSVCMECEG TEALWICLIC GHIGCGRYQG GHAASHYRTT NHTYALQLGT
     NRVWDYAGDN FVHRLLQSKS DGKLVATQSP GGDDGEEKID SMQLEFTYLL TSQLDAQRDY
     YEERLSRLES IICGERQKLQ EDHEQAKQKT AQLEVKLHAL TKEKNSLERK VSQLTSKLGT
     VLGELAEEKQ FGKTLQANQV TWQNKFTTLE KQCTEKEQEI VELKEQVRDL MFYMEAQNTI
     AGSELKSELV DGTVVLPADA VAAASSISAS GAFAASTSAG GAKAKRRQRR K
//